Razavi Mohammad Etezad, Rajabi Mohammad Taher, Hassanpoor Narges, Mohammadi S Saeed
Mashhad Eye Research Center, Khatam Alanbia Eye Hospital, Mashhad University of Medical Sciences, Mashhad, Iran.
Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
J Curr Ophthalmol. 2019 Jan 30;31(2):214-217. doi: 10.1016/j.joco.2019.01.002. eCollection 2019 Jun.
To assess the efficacy of sclerotherapy with sodium tetradecyl sulfate (STS; Fibrovein 1%) in superficial periocular venous and lymphatic malformations.
Eleven patients with low-flow venous and lymphatic malformations with extension predominantly to the eyelids, conjunctiva, and anterior orbit were selected. Sclerotherapy with STS was undertaken as an office-based procedure without any radiological guidance. Injections were repeated every 4 weeks until desired response occurred. Therapeutic effect was assessed objectively by change in the size of the lesions in serial photography.
The lesions completely resolved in 4 cases with small eyelid and fornix lesions. In other 7 cases there was partial resolution to less than half of primary size. We did not have any significant complications.
Sclerotherapy with STS is an easy and effective modality for treatment of venous-lymphatic malformations and can be undertaken as an office-based procedure in lesions which are limited to eyelids and anterior orbit.
评估十四烷基硫酸钠（STS；1% Fibrovein）硬化疗法治疗眼周浅表静脉和淋巴管畸形的疗效。
选取11例主要累及眼睑、结膜和眶前部的低流量静脉和淋巴管畸形患者。在无任何放射学引导的情况下，于门诊进行STS硬化疗法。每4周重复注射，直至出现预期反应。通过连续摄影中病变大小的变化客观评估治疗效果。
4例眼睑和穹窿部小病变患者的病变完全消退。其他7例患者病变部分消退至小于原始大小的一半。未出现任何严重并发症。
STS硬化疗法是治疗静脉-淋巴管畸形的一种简便有效的方法，对于局限于眼睑和眶前部的病变可在门诊进行。
