Jin Ki Won, Shin Young Joo, Hyon Joon Young
Department of Ophthalmology, Hallym University College of Medicine, Gangnam Sungshim Hospital, 948-1 Daerim1-dong, Youngdeungpo-gu, Seoul, 150-950, South Korea.
Department of Ophthalmology, Seoul National University College of Medicine, Seoul, South Korea.
BMC Ophthalmol. 2017 Mar 31;17(1):36. doi: 10.1186/s12886-017-0426-2.
A chalazion is a common eyelid disease that causes eye morbidity due to inflammation and cosmetic disfigurement. Corneal topographic changes are important factors in corneal refractive surgery, intraocular lens power calculations for cataract surgery, and visual acuity assessments. However, the effects of chalazia on corneal astigmatism have not been thoroughly investigated. The changes in corneal astigmatism according to chalazion size and location is necessary for better outcome of ocular surgery. The aim of this study is to evaluate changes in corneal astigmatism according to chalazion size and location.
In this cross-sectional study, a total of 44 eyes from 33 patients were included in the chalazion group and 70 eyes from 46 patients comprised the control group. Chalazia were classified according to location and size. An autokeratorefractometer (KR8100, Topcon; Japan) and a Galilei™ dual-Scheimpflug analyzer (Ziemer Group; Port, Switzerland) were utilized to evaluate corneal changes.
Oblique astigmatism was greater in the chalazion group compared with the control group (p < 0.05). Astigmatism by simulated keratometry (simK), steep K by simK, total root mean square, second order aberration, oblique astigmatism, and vertical astigmatism were significantly greater in the upper eyelid group (p < 0.05). Astigmatism by simK, second order aberration, oblique astigmatism, and vertical astigmatism were significantly greater in the large-sized chalazion group (p < 0.05). Corneal wavefront aberration was the greatest in the upper eyelid chalazion group, whole area group, and large-sized chalazion group (p < 0.05).
Large-sized chalazia in the whole upper eyelid should be treated in the early phase because they induced the greatest change in corneal topography. Chalazion should be treated before corneal topography is performed preoperatively and before the diagnosis of corneal diseases.
睑板腺囊肿是一种常见的眼睑疾病，可因炎症和外观毁损导致眼部发病。角膜地形图变化是角膜屈光手术、白内障手术人工晶状体屈光度计算及视力评估中的重要因素。然而，睑板腺囊肿对角膜散光的影响尚未得到充分研究。根据睑板腺囊肿的大小和位置了解角膜散光的变化对于提高眼科手术效果很有必要。本研究旨在评估根据睑板腺囊肿大小和位置的角膜散光变化。
在这项横断面研究中，睑板腺囊肿组共纳入33例患者的44只眼，对照组由46例患者的70只眼组成。睑板腺囊肿根据位置和大小进行分类。使用自动角膜验光仪（KR8100，拓普康；日本）和Galilei™双Scheimpflug分析仪（齐默集团；瑞士波特）评估角膜变化。
睑板腺囊肿组的斜轴散光大于对照组（p < 0.05）。上睑组的模拟角膜曲率计（simK）散光、simK陡峭角膜曲率、总均方根、二阶像差、斜轴散光和垂直散光显著更大（p < 0.05）。大尺寸睑板腺囊肿组的simK散光、二阶像差、斜轴散光和垂直散光显著更大（p < 0.05）。上睑睑板腺囊肿组、全区域组和大尺寸睑板腺囊肿组的角膜波前像差最大（p < 0.05）。
整个上睑的大尺寸睑板腺囊肿应尽早治疗，因为它们会引起角膜地形图的最大变化。睑板腺囊肿应在术前进行角膜地形图检查之前以及角膜疾病诊断之前进行治疗。
