Gomber Sunil, Arora Vanny, Dewan Pooja
Department of Pediatrics, University College of Medical Sciences and Guru Teg Bahadur Hospital, Dilshad Garden, Delhi 110095, India. Correspondence to: Dr Sunil Gomber, Director-Professor, Department of Pediatrics, Guru Teg Bahadur Hospital, Dilshad Garden. Delhi 110 095, India.
Indian Pediatr. 2017 Mar 15;54(3):241-242. doi: 10.1007/s13312-017-1038-x.
Oral polio vaccine can rarely lead to Vaccine-associated paralytic poliomyelitis (VAPP).
A 2-year-old child with asymmetric paralysis of lower limbs following first booster of oral polio vaccine; type 2 Vaccine-derived poliovirus (VDPV) isolated. Subsequently, the child was diagnosed to have common variable immunodeficiency.
Paralysis gradually improved on follow-up; monthly intravenous immunoglobulin therapy started for primary immunodeficiency.
We need to evaluate children with VAPP for underlying immunodeficiency.
