Edeani Francis, Malik Adeel, Kaul Ajay
Department of Internal Medicine, Good Samaritan Hospital, Cincinnati, OH, 45220, USA.
Neurogastroenterology and Motility Disorders Program, Division of Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, 3333 Burnet Avenue, Cincinnati, OH, 45229, USA.
Curr Gastroenterol Rep. 2017 Mar;19(3):13. doi: 10.1007/s11894-017-0549-x.
The Chicago classification was based on metrics derived from studies in asymptomatic adult subjects. Our objectives were to characterize esophageal motility disorders in children and to determine whether the spectrum of manometric findings is similar between the pediatric and adult populations.
Studies have suggested that the metrics utilized in manometric diagnosis depend on age, size, and manometric assembly. This would imply that a different set of metrics should be used for the pediatric population. There are no standardized and generally accepted metrics for use in the pediatric population, though there have been attempts to establish metrics specific to this population. Overall, we found that the distribution of esophageal motility disorders in children was like that described in adults using the Chicago classification. This analysis will serve as a prequel to follow-up studies exploring the individual metrics for variability among patients, with the objective of establishing novel metrics for the pediatric population.
芝加哥分类法基于对无症状成年受试者的研究得出的指标。我们的目标是描述儿童食管动力障碍,并确定测压结果在儿科和成人人群中的谱是否相似。
研究表明,测压诊断中使用的指标取决于年龄、体型和测压设备。这意味着应该为儿科人群使用不同的指标集。尽管已经尝试建立针对该人群的指标,但目前尚无用于儿科人群的标准化且普遍接受的指标。总体而言,我们发现儿童食管动力障碍的分布与使用芝加哥分类法描述的成人情况相似。该分析将作为后续研究的前奏,后续研究将探索患者间变异性的个体指标,目的是为儿科人群建立新的指标。