Yoshida Tadao, Sone Michihiko, Kitoh Ryosuke, Nishio Shin-Ya, Ogawa Kaoru, Kanzaki Sho, Hato Naohito, Fukuda Satoshi, Hara Akira, Ikezono Tetsuo, Ishikawa Kotaro, Iwasaki Satoshi, Kaga Kimitaka, Kakehata Seiji, Matsubara Atsushi, Matsunaga Tatsuo, Murata Takaaki, Naito Yasushi, Nakagawa Takashi, Nishizaki Kazunori, Noguchi Yoshihiro, Sano Hajime, Sato Hiroaki, Suzuki Mikio, Shojaku Hideo, Takahashi Haruo, Takeda Hidehiko, Tono Testuya, Yamashita Hiroshi, Yamasoba Tatsuya, Usami Shin-Ichi
a Department of Otorhinolaryngology , Nagoya University, Graduate School of Medicine , Nagoya , Japan.
b Department of Otorhinolaryngology , Shinshu University School of Medicine , Matsumoto , Japan.
Acta Otolaryngol. 2017;137(sup565):S38-S43. doi: 10.1080/00016489.2017.1297539. Epub 2017 Apr 1.
The aim of this study was to investigate the differences between idiopathic sudden sensorineural hearing loss (SSNHL), and acute low-tone sensorineural hearing loss (ALHL) using the results of a nationwide survey database in Japan and to analyze the variables associated with their clinical features and the severity of hearing impairment, treatment, and prognosis.
Participants were patients registered between April 2014 and March 2016 in a multicenter epidemiological survey database involving 30 university hospitals and medical centers across Japan. Statistical analysis was performed to clarify the factors associated with their clinical characteristics and the severity of hearing impairment, treatment, and prognosis.
Idiopathic SSNHL and ALHL differed significantly in terms of male-to-female ratio, age distribution, and time from onset to start of treatment. The treatment methods and hearing prognosis also differed markedly between the two diseases. A majority (92%) of idiopathic SSNHL patients were administered some type of corticosteroid, while half of the ALHL patients received corticosteroids and a diuretic agent.
The results suggested that idiopathic SSNHL and ALHL belonged to different categories of inner ear disease.
本研究旨在利用日本全国性调查数据库的结果，调查特发性突发性感音神经性听力损失（SSNHL）与急性低频感音神经性听力损失（ALHL）之间的差异，并分析与它们的临床特征、听力损害严重程度、治疗及预后相关的变量。
研究对象为2014年4月至2016年3月期间登记在一个多中心流行病学调查数据库中的患者，该数据库涵盖了日本全国30家大学医院和医疗中心。进行统计分析以阐明与它们的临床特征、听力损害严重程度、治疗及预后相关的因素。
特发性SSNHL和ALHL在男女比例、年龄分布以及从发病到开始治疗的时间方面存在显著差异。两种疾病的治疗方法和听力预后也明显不同。大多数（92%）特发性SSNHL患者接受了某种类型的皮质类固醇治疗，而一半的ALHL患者接受了皮质类固醇和利尿剂治疗。
结果表明，特发性SSNHL和ALHL属于不同类别的内耳疾病。
