Yoon Chul Young, Kong Tae Hoon, Lee Juhyung, Seo Young Joon, Ahn Jae Joon
Research Institute of Hearing Enhancement, Yonsei University Wonju College of Medicine, Wonju, South Korea.
Department of Otorhinolaryngology, Yonsei University Wonju College of Medicine, 20 Ilsan-Ro, Wonju, Gangwon-Do, 26426, South Korea.
Eur Arch Otorhinolaryngol. 2023 May;280(5):2181-2190. doi: 10.1007/s00405-022-07693-0. Epub 2022 Oct 14.
Idiopathic sudden sensorineural hearing loss (ISSNHL) is a medical emergency, and delayed treatment can have permanent sequelae. However, the etiology of ISSNHL is diverse and unclear; thus, it is idiopathic. To develop an insight into this condition, patients with ISSNHL must be clearly identified. We propose an operational definition for the unambiguous identification of ISSNHL patients. Patients are identified through suggested definitions, and prevalence and general information are investigated.
A retrospective study of patients with ISSNHL was performed using the Health Insurance and Review Assessment-National Patient Sample from 2009 to 2016. To present a new operational definition, a systematic review was conducted for studies on ISSNHL from January 2007 to June 2021. After constructing several operant definitions using the conditions that can specify patients with ISSNHL in big data, we compared each definition to propose an operational definition.
The important conditions required to classify patients with ISSNHL using big data were the International Classification of Diseases (ICD)-10 code, number of pure tone audiometry (PTA) tests, and whether steroids were prescribed. Among them, those who had undergone PTA tests more than twice could be clearly identified as patients with ISSNHL.
As the use of big data becomes smoother, research using national medical data is being conducted; however, the results of the studies may vary depending on how a patient with ISSNHL is classified. Clear identification of patients with ISSNHL will be beneficial for better management of this condition.
特发性突发性感音神经性听力损失(ISSNHL)是一种医疗急症,延迟治疗可能会导致永久性后遗症。然而,ISSNHL的病因多种多样且尚不明确,因此属于特发性。为深入了解这种疾病,必须明确识别出ISSNHL患者。我们提出了一个用于明确识别ISSNHL患者的操作性定义。通过建议的定义来识别患者,并对患病率和一般信息进行调查。
利用2009年至2016年的健康保险审查评估-全国患者样本对ISSNHL患者进行回顾性研究。为了提出一个新的操作性定义,对2007年1月至2021年6月间关于ISSNHL的研究进行了系统综述。在利用大数据中可明确ISSNHL患者的条件构建了几个操作性定义后,我们对每个定义进行比较以提出一个操作性定义。
使用大数据对ISSNHL患者进行分类所需的重要条件是国际疾病分类(ICD)-10编码、纯音听力测定(PTA)测试的次数以及是否开具了类固醇药物。其中,接受PTA测试超过两次的患者可被明确识别为ISSNHL患者。
随着大数据使用的日益顺畅,利用国家医疗数据的研究正在开展;然而,研究结果可能因ISSNHL患者的分类方式而异。明确识别ISSNHL患者将有助于更好地管理这种疾病。