Çelebi Sözener Zeynep, Mısırlıgil Mehmet, Çerçi Pamir, Aydın Ömür, Kendirlinan Reşat, Sin Betül, Mısırlıgil Zeynep
Department of Immunology and Allergy, Faculty of Medicine, Ankara University, Ankara, Turkey.
Tuberk Toraks. 2016 Dec;64(4):269-274.
It is known that viral infections trigger exacerbations in asthma patients.There are conflicting reports on whether influenza vaccine is preventive or not. In this study, we aimed to evaluate asthmatic patient's attitude towards influenza vaccine and to determine which factors affect this attitude.
A questionnaire involving data about demographic information, co-morbidities, frequency of viral upper respiratory tract infections, subject's influenza vaccination status and attitude towards vaccination had been filled for our outpatient clinic asthma patients and also for healthy controls. Results were evaluated separately for the two groups and then compared to each other.
For the study; 108 asthma patients (91 female, 17 male) and 110 non-asthmatic controls (64 female, 46 male) were enrolled. In asthma group, vaccination rates were significantly higher in the previous year (40.7%) and nearly half of them stated that they do regularly have influenza shots every year. Contrast to this find; half of the patients in the control group stated that they do not need to vaccinate themselves and 26.2% said that they don't believe influenza vaccine has any preventive effect. Also in the asthma group, this ratio was similar to the control group (20.3%). In asthma group, 66.7% of the patients who had side effects at their previous shots did not want to vaccinate themselves this year (p= 0.02). More than a half of the patients (53.1%) whom did not have shots had an episode of viral upper respiratory tract infection this year and this rate was significantly lower in the vaccinated group (p= 0.00). This result highlights the preventive effect of vaccination.
We found that asthma patients' knowledge on influenza infection and vaccine were insufficient and also their belief towards the preventive features of the vaccination was low. Informing and encouraging patients about preventive medicine through various activities and meetings would be crucial.
众所周知,病毒感染会引发哮喘患者病情加重。关于流感疫苗是否具有预防作用,存在相互矛盾的报道。在本研究中,我们旨在评估哮喘患者对流感疫苗的态度,并确定哪些因素会影响这种态度。
为我们门诊的哮喘患者以及健康对照者填写了一份问卷,问卷内容包括人口统计学信息、合并症、病毒性上呼吸道感染频率、受试者的流感疫苗接种状况以及对疫苗接种的态度。分别对两组的结果进行评估,然后相互比较。
本研究纳入了108例哮喘患者(91例女性,17例男性)和110例非哮喘对照者(64例女性,46例男性)。在哮喘组中,上一年的疫苗接种率显著更高(40.7%),并且其中近一半的患者表示他们每年都会定期接种流感疫苗。与这一发现形成对比的是,对照组中有一半的患者表示他们无需接种疫苗,26.2%的患者表示他们不相信流感疫苗有任何预防作用。在哮喘组中,这一比例与对照组相似(20.3%)。在哮喘组中,上一次接种出现副作用的患者中有66.7%今年不想接种疫苗(p = 0.02)。未接种疫苗的患者中超过一半(53.1%)今年发生了病毒性上呼吸道感染,而接种组的这一比例显著更低(p = 0.00)。这一结果凸显了疫苗接种的预防作用。
我们发现哮喘患者对流感感染和疫苗的了解不足,并且他们对疫苗接种预防特性的信任度较低。通过各种活动和会议向患者宣传和鼓励预防医学知识至关重要。