肠易激综合征中原发性干燥综合征和纤维肌痛的发生率
The Frequency of Primary Sjogren's Syndrome and Fibromyalgia in Irritable Bowel Syndrome.
作者信息
Erbasan Funda, Cekin Yesim, Coban Deniz Turgut, Karasu Ugur, Suren Dinc, Cekin Ayhan H
机构信息
Funda Erbasan, MD. Specialist, Department of Rheumatology, Antalya Training and Research Hospital, Antalya, Turkey.
Yesim Cekin, MD. Associate Professor, Department of Microbiology, Antalya Training and Research Hospital, Antalya, Turkey.
出版信息
Pak J Med Sci. 2017 Jan-Feb;33(1):137-141. doi: 10.12669/pjms.331.11168.
OBJECTIVE
To determine the frequency of sicca complex, Sjogren's Syndrome (SS) and Fibromyalgia (FM) in patients with Irritable Bowel Syndrome (IBS).
METHODS
Seventy seven IBS patients who fulfilled the Rome-III criteria were included in the study. All patients were assessed for FM according to the American College of Rheumatology (ACR) 2010 criteria. After examination for objective evidence of sicca complex by Schirmer test, TBUT and Ocular Staining Score (OSS), serological tests were performed. And the diagnosis of SS was made according to the American College of Rheumatology (ACR) classification criteria for SS - 2012.
RESULTS
Thirteen (16.9%) of IBS patients had FM. Dry eye was detected in 20(26.0%), 7(9.1%) and 29(37.7%) patients by OSS, Schirmer test and TBUT, respectively. Of 77 patients with IBS, the diagnosis of SS was established in two patients (2.6%).
CONCLUSION
The frequency of Sjogren's Syndrome among patients with IBS is relatively higher than the general population. All IBS patients should be questioned for dryness of the mouth and eyes, and if necessary, should be evaluated for SS.
目的
确定肠易激综合征（IBS）患者中干燥综合征、干燥综合征（SS）和纤维肌痛（FM）的发生率。
方法
纳入77例符合罗马III标准的IBS患者。所有患者均根据美国风湿病学会（ACR）2010年标准评估FM。通过Schirmer试验、泪膜破裂时间（TBUT）和眼表染色评分（OSS）检查干燥综合征的客观证据后，进行血清学检查。并根据美国风湿病学会（ACR）2012年SS分类标准做出SS诊断。
结果
13例（16.9%）IBS患者患有FM。通过OSS、Schirmer试验和TBUT分别检测出20例（26.0%）、7例（9.1%）和29例（37.7%）患者存在干眼。在77例IBS患者中，2例（2.6%）确诊为SS。
结论
IBS患者中干燥综合征的发生率相对高于一般人群。所有IBS患者均应询问口干、眼干情况，必要时应评估是否患有SS。
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