Nakamura Keiki, Hamba Hidenori, Nakashima Syozi, Sadr Alireza, Nikaido Toru, Oikawa Masakazu, Uo Motohiro, Tagami Junji
Department of Cariology and Operative Dentistry, Division of Oral Health Sciences, Graduate School of Medical and Dental Science, Tokyo Medical and Dental University (TMDU).
Department of Endodontics and Clinical Cariology, Tokyo Dental College.
Dent Mater J. 2017 Jul 26;36(4):482-490. doi: 10.4012/dmj.2016-303. Epub 2017 Mar 29.
This study aimed to evaluate the inhibitory effect of experimental pastes containing surface pre-reacted glass ionomer (S-PRG) fillers on enamel demineralization. Bovine blocks were treated twice a day for 4 days by 7 groups; experimental pastes containing 0-30 wt% S-PRG filler (S00, S01, S05, S10, and S30), deionized water (DW) as negative control, and NaF paste (MP) as positive control. The surfaces were demineralized by acetic acid for 3 days. Mineral loss (ML) was calculated by micro-computed X-ray tomography. The treated surface was finally investigated with scanning electron microscope (SEM) and micro-focused particle induced X-ray emission (micro-PIXE). S05, S10 and S30 demonstrated significantly lower ML than S00, S01 and DW (p<0.05). S10 showed the greatest inhibitory effect, which was significantly greater than MP. The S-PRG filler containing experimental pastes demonstrated a potential to inhibit enamel demineralization. Sr ion incorporation was confirmed on the enamel surface with the experimental pastes.
本研究旨在评估含表面预反应玻璃离子（S-PRG）填料的实验性糊剂对牙釉质脱矿的抑制作用。将牛牙块分为7组，每天处理两次，共处理4天；分别使用含0-30 wt% S-PRG填料的实验性糊剂（S00、S01、S05、S10和S30）、去离子水（DW）作为阴性对照、氟化钠糊剂（MP）作为阳性对照。用乙酸使表面脱矿3天。通过微计算机X射线断层扫描计算矿物质损失（ML）。最后用扫描电子显微镜（SEM）和微聚焦粒子诱导X射线发射（micro-PIXE）对处理过的表面进行研究。S05、S10和S30的ML显著低于S00、S01和DW（p<0.05）。S10显示出最大的抑制作用，显著大于MP。含S-PRG填料的实验性糊剂显示出抑制牙釉质脱矿的潜力。通过实验性糊剂在牙釉质表面证实了锶离子的掺入。
