Graduate School of Sports and Health Science, Ritsumeikan University, Kusatsu, Japan.
Faculty of Sports and Health Science, Ritsumeikan University, Kusatsu, Japan.
J Strength Cond Res. 2018 Apr;32(4):1053-1062. doi: 10.1519/JSC.0000000000001911.
Sumi, D, Kojima, C, and Goto, K. Impact of endurance exercise in hypoxia on muscle damage, inflammatory and performance responses. J Strength Cond Res 32(4): 1053-1062, 2018-This study evaluated muscle damage and inflammatory and performance responses after high-intensity endurance exercise in moderate hypoxia among endurance athletes. Nine trained endurance athletes completed 2 different trials on different days: exercise under moderate hypoxia (H trial, FiO2 = 14.5%) and normoxia (N trial, FiO2 = 20.9%). They performed interval exercises (10 × 3-minute running at 95% of V[Combining Dot Above]O2max with 60-second of active rest at 60% of V[Combining Dot Above]O2max) followed by 30-minute of continuous running at 85% of V[Combining Dot Above]O2max under either hypoxic or normoxic conditions. Venous blood samples were collected 4 times: before exercise, 0, 60, and 120-minute after exercise. The time to exhaustion (TTE) during running at 90% of V[Combining Dot Above]O2max was also determined to evaluate endurance capacity 120-minute after the training session. The H trial induced a significantly greater exercise-induced elevation in the blood lactate concentration than did the N trial (p = 0.02), whereas the elevation in the exercise-induced myoglobin concentration (muscle damage marker) was significantly greater in the N trial than in the H trial (p = 0.005). There was no significant difference in plasma interleukin-6 (inflammatory marker) concentration between the H and N trials. The TTE was shorter in the N trial (613 ± 65 seconds) than in the H trial (783 ± 107 seconds, p = 0.02). In conclusion, among endurance athletes, endurance exercise under moderate hypoxic conditions did not facilitate an exercise-induced muscle damage response or cause a further reduction in the endurance capacity compared with equivalent exercise under normoxic conditions.
本文研究了在中低氧环境下进行高强度耐力运动对耐力运动员肌肉损伤、炎症和运动表现的影响。9 名训练有素的耐力运动员在不同的日子进行了 2 次不同的试验：在中低氧（FiO2=14.5%）和常氧（FiO2=20.9%）条件下进行高强度耐力运动。他们进行了间隔训练（10 次 3 分钟的跑步，强度为 95%的最大摄氧量，60 秒的主动休息，强度为 60%的最大摄氧量），随后在 85%的最大摄氧量下进行 30 分钟的连续跑步，无论在低氧还是常氧条件下。在运动前、运动后 0、60 和 120 分钟采集静脉血样。还测定了在 90%的最大摄氧量下跑步的运动至力竭时间（TTE），以评估训练结束后 120 分钟的耐力能力。与常氧试验相比，低氧试验引起的运动后血乳酸浓度升高显著更大（p=0.02），而运动后肌红蛋白浓度升高（肌肉损伤标志物）在常氧试验中显著大于低氧试验（p=0.005）。低氧和常氧试验之间的血浆白细胞介素-6（炎症标志物）浓度没有显著差异。常氧试验中的 TTE 更短（613±65 秒），而低氧试验中的 TTE 更长（783±107 秒，p=0.02）。综上所述，对于耐力运动员而言，与常氧条件下的等效运动相比，中低氧条件下的耐力运动并没有促进运动引起的肌肉损伤反应，也没有进一步降低耐力能力。
