Edington N, Broad S, Wrathall A E, Done J T
Department of Microbiology and Parasitology, Royal Veterinary College, London, Gt. Britain.
Vet Microbiol. 1988 Feb;16(2):189-93. doi: 10.1016/0378-1135(88)90043-0.
Four sows with circulating antibody were exposed to porcine cytomegalovirus. Virus was detected in 8 of 24 foetuses by immunofluorescence and/or virus isolation from 2 sows with low levels of antibody. In 6 of the infected foetuses, the virus was in capillary endothelium and macrophages of the lung, and was associated with interlobular oedema in 2 of these. Virus was also detected in the nasal mucosa, spleen and brain. The majority of the virus-positive foetuses were grossly normal.
将4头具有循环抗体的母猪暴露于猪巨细胞病毒。通过免疫荧光和/或病毒分离，在24头胎儿中的8头检测到病毒，这2头母猪抗体水平较低。在6头受感染的胎儿中，病毒存在于肺的毛细血管内皮细胞和巨噬细胞中，其中2头伴有小叶间水肿。在鼻黏膜、脾脏和大脑中也检测到病毒。大多数病毒阳性胎儿大体正常。
