Edington N, Wrathall A E, Done J T
Royal Veterinary College, Department of Microbiology and Parasitology, London, Gt. Britain.
Vet Microbiol. 1988 Jun;17(2):117-28. doi: 10.1016/0378-1135(88)90003-x.
Following intranasal exposure to PCMV at or within 48 h of coitus transplacental infection occurred in two groups of gilts. Five out of 22 embryos were infected in the first group but only 2 out of 63 in the second. A more rapid immune response as measured by circulating antibody was probably instrumental in abrogating infection in the second group. In the infected embryos the virus localized in leptomeningeal cells, hepatic sinusoidal cells, peritoneal macrophages, periosteal cells and occasional alveolar cells, but the placenta did not appear to be a primary site of viral replication.
在两组后备母猪中，在交配后48小时内或48小时经鼻暴露于猪巨细胞病毒（PCMV）后发生了经胎盘感染。第一组22个胚胎中有5个被感染，但第二组63个胚胎中只有2个被感染。通过循环抗体测量的更快免疫反应可能有助于消除第二组中的感染。在受感染的胚胎中，病毒定位于软脑膜细胞、肝窦状细胞、腹膜巨噬细胞、骨膜细胞和偶尔的肺泡细胞中，但胎盘似乎不是病毒复制的主要部位。
