食管次全切除术后喉返神经麻痹的短期和长期进展
Short- and Long-term Progress of Recurrent Laryngeal Nerve Paralysis After Subtotal Esophagectomy.
作者信息
Shimizu Hiroki, Shiozaki Atsushi, Fujiwara Hitoshi, Konishi Hirotaka, Kosuga Toshiyuki, Komatsu Shuhei, Ichikawa Daisuke, Okamoto Kazuma, Otsuji Eigo
机构信息
Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Division of Digestive Surgery, Department of Surgery, Kyoto Prefectural University of Medicine, Kyoto, Japan
出版信息
Anticancer Res. 2017 Apr;37(4):2019-2023. doi: 10.21873/anticanres.11546.
AIM
To clarify risk factors and long-term progress of postoperative recurrent laryngeal nerve paralysis (PRNP) in patients with esophageal cancer.
PATIENTS AND METHODS
One hundred and twenty-five esophageal cancer patients, who underwent subtotal esophagetomy, including recurrent laryngeal nerve lymphadenectomy, were analyzed. A laryngoscopy was routinely performed to assess the motility of vocal cords.
RESULTS
PRNP was detected in 79 patients and 26 (20.8%) patients required medical interventions (Grade II or more by the Clavien-Dindo classification; group II). Forty-one of 66 (62.1%) patients recovered from PRNP with a median postoperative time of 135 days. The three-field lymphadenectomy and long operative time were the independent prognostic factors of group II.
CONCLUSION
Radical operation caused PRNP with grade II or more. The long-term follow-up of vocal cords was necessary to detect patients with either transient or permanent PRNP.
目的
明确食管癌患者术后喉返神经麻痹（PRNP）的危险因素及长期进展情况。
患者与方法
对125例行食管次全切除术（包括喉返神经淋巴结清扫术）的食管癌患者进行分析。常规行喉镜检查以评估声带活动度。
结果
79例患者检测出PRNP，26例（20.8%）患者需要医疗干预（根据Clavien-Dindo分类为II级或更高；II组）。66例患者中的41例（62.1%）PRNP恢复，术后中位时间为135天。三野淋巴结清扫术和手术时间长是II组的独立预后因素。
结论
根治性手术导致II级或更高等级的PRNP。对声带进行长期随访对于发现短暂性或永久性PRNP患者很有必要。
Zotero 插件