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Clinicopathological features and surgical treatment of gastric cancer in South Korea: the results of 2009 nationwide survey on surgically treated gastric cancer patients.韩国胃癌的临床病理特征和外科治疗:2009 年全国胃癌手术患者调查结果。
J Gastric Cancer. 2011 Jun;11(2):69-77. doi: 10.5230/jgc.2011.11.2.69. Epub 2011 Jun 30.
2
Impact of age on outcome after colorectal cancer surgery in the elderly - a developing country perspective.年龄对老年人大肠癌手术后结局的影响——以一个发展中国家的视角
BMC Surg. 2011 Aug 17;11:17. doi: 10.1186/1471-2482-11-17.
3
Minimally invasive surgery for gastric cancer: the future standard of care.胃癌的微创手术:未来的治疗标准。
World J Surg. 2011 Jul;35(7):1469-77. doi: 10.1007/s00268-011-1051-5.
4
Morbidity and mortality of laparoscopic gastrectomy versus open gastrectomy for gastric cancer: an interim report--a phase III multicenter, prospective, randomized Trial (KLASS Trial).腹腔镜与开腹胃癌根治术的近期疗效比较——一项 III 期多中心前瞻性随机对照临床试验(KLASS 试验)
Ann Surg. 2010 Mar;251(3):417-20. doi: 10.1097/SLA.0b013e3181cc8f6b.
5
Multicentre study of the safety of laparoscopic subtotal gastrectomy for gastric cancer in the elderly.老年胃癌患者腹腔镜次全胃切除术安全性的多中心研究
Br J Surg. 2009 Dec;96(12):1437-42. doi: 10.1002/bjs.6777.
6
The Clavien-Dindo classification of surgical complications: five-year experience.手术并发症的Clavien-Dindo分类:五年经验
Ann Surg. 2009 Aug;250(2):187-96. doi: 10.1097/SLA.0b013e3181b13ca2.
7
Actual 3-year survival after laparoscopy-assisted gastrectomy for gastric cancer.腹腔镜辅助胃癌根治术后的实际3年生存率
Arch Surg. 2009 Jun;144(6):559-64; discussion 565. doi: 10.1001/archsurg.2009.110.
8
Risk factors for operative complications in elderly patients during laparoscopy-assisted gastrectomy.老年患者腹腔镜辅助胃切除术手术并发症的危险因素
J Am Coll Surg. 2009 Feb;208(2):186-92. doi: 10.1016/j.jamcollsurg.2008.10.023. Epub 2008 Dec 18.
9
Improved quality of life outcomes after laparoscopy-assisted distal gastrectomy for early gastric cancer: results of a prospective randomized clinical trial.腹腔镜辅助远端胃癌根治术治疗早期胃癌后生活质量改善:一项前瞻性随机临床试验的结果
Ann Surg. 2008 Nov;248(5):721-7. doi: 10.1097/SLA.0b013e318185e62e.
10
Does age matter in the indication for laparoscopy-assisted gastrectomy?腹腔镜辅助胃切除术的适应证中年龄重要吗?
J Gastrointest Surg. 2008 Sep;12(9):1502-7. doi: 10.1007/s11605-008-0567-y. Epub 2008 Jul 3.

腹腔镜辅助远端胃切除术治疗老年早期胃癌。

Laparoscopy-assisted distal gastrectomy for early gastric cancer in the elderly.

机构信息

Department of Surgery, Kosin University College of Medicine, Busan, Korea.

出版信息

J Gastric Cancer. 2012 Dec;12(4):232-6. doi: 10.5230/jgc.2012.12.4.232. Epub 2012 Dec 31.

DOI:10.5230/jgc.2012.12.4.232
PMID:23346495
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3543973/
Abstract

PURPOSE

With an increase in life expectancy, more elderly patients are presenting with gastric cancer. As a result it is yet be resolved whether laparoscopy assisted distal gastrectomy is a suitable treatment for elderly patients with early gastric cancer. This study retrospectively compared surgical outcomes of laparoscopy assisted distal gastrectomy between elderly and nonelderly patients with gastric cancer.

MATERIALS AND METHODS

The study group was comprised of 316 patients who underwent laparoscopy assisted distal gastrectomy between April 2005 and December 2010. Of these patients, 93 patients whose ages were 65 years or more were compared with 223 patients who were younger.

RESULTS

There were no differences in the short term outcome or minor complication rate between the elderly patients and the nonelderly patients. The hospital stay was significantly longer and the major complication rate was significantly higher for the elderly patients compared with nonelderly patients.

CONCLUSIONS

Laparoscopy assisted distal gastrectomy for early gastric cancer in the elderly patients had comparable operation time and blood loss with the nonelderly group. However, the safety and advantage of laparoscopy assisted distal gastrectomy in the elderly patients need to be further studied in higher volume trials.

摘要

目的

随着预期寿命的延长,越来越多的老年患者出现胃癌。因此,腹腔镜辅助远端胃切除术是否适合老年早期胃癌患者仍未得到解决。本研究回顾性比较了腹腔镜辅助远端胃切除术治疗老年和非老年胃癌患者的手术结果。

材料和方法

研究组包括 2005 年 4 月至 2010 年 12 月期间接受腹腔镜辅助远端胃切除术的 316 例患者。其中,93 例年龄在 65 岁及以上的患者与 223 例年龄较小的患者进行了比较。

结果

老年患者与非老年患者的短期结果或轻微并发症发生率无差异。与非老年患者相比,老年患者的住院时间明显延长,且主要并发症发生率明显更高。

结论

对于老年早期胃癌患者,腹腔镜辅助远端胃切除术的手术时间和出血量与非老年组相当。然而,在更高容量的试验中,需要进一步研究腹腔镜辅助远端胃切除术在老年患者中的安全性和优势。