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外阴硬化性苔藓的评估

An assessment of vulval lichen sclerosus.

作者信息

Jones I S

出版信息

Aust N Z J Obstet Gynaecol. 1978 Aug;18(3):185-9. doi: 10.1111/j.1479-828x.1978.tb00046.x.

Abstract

Vulval lichen sclerosus (L.S.) has been assessed clinically, colposcopically, and histologically to ascertain the suitability of including this condition in the nomenclature proposed by the International Society for the Study of Vulval Disease (I.S.S.V.D). In many cases the macroscopic appearance of lichen sclerosus is characteristic, but this is not always the case. Histologically, the appearances of the dermal hyaline change, the reduction in the length and the number of rete pegs, to a lesser extent thinning of the dermis and sometimes thinning of the epidermis are characteristics. The presence of dermal inflammatory cells and changes in the thickness of the keratin layer are, however, much more variable. Exact measurements of the various layers of the vulval skin are not necessary in the routine assessment of lichen sclerosus. The present study justifies the inclusion of lichen sclerosus on histological criteria in the I.S.S.V.D.'s nomenclature.

摘要

已通过临床、阴道镜及组织学评估外阴硬化性苔藓(L.S.),以确定将此病纳入国际外阴疾病研究学会(I.S.S.V.D.)提议的命名法是否合适。在许多病例中,硬化性苔藓的宏观表现具有特征性,但情况并非总是如此。组织学上,真皮透明样变、 rete 钉长度和数量减少、真皮程度较轻的变薄以及有时表皮变薄是其特征。然而,真皮炎症细胞的存在和角质层厚度的变化则更具变异性。在硬化性苔藓的常规评估中,无需对外阴皮肤各层进行精确测量。本研究证明根据组织学标准将硬化性苔藓纳入I.S.S.V.D.的命名法是合理的。

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