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使用可调谐声学梯度透镜的快速轴向扫描光声显微镜。

Fast axial-scanning photoacoustic microscopy using tunable acoustic gradient lens.

作者信息

Yang Xiaoquan, Jiang Bowen, Song Xianlin, Wei Jianshuang, Luo Qingming

出版信息

Opt Express. 2017 Apr 3;25(7):7349-7357. doi: 10.1364/OE.25.007349.

Abstract

An optical-resolution photoacoustic microscope (OR-PAM) with capability of fast axial-scanning was developed by using a tunable acoustic gradient (TAG) lens. The TAG lens was designed to continuously changing the focal plane of OR-PAM by modulating its refractive power with fast-changing ultrasonic standing wave. The performance was shown by imaging a carbon fiber. We achieved a DoF of about 750 μm. The head of a zebrafish was also imaged to further demonstrate the feasibility of our method.

摘要

通过使用可调谐声学梯度(TAG)透镜,开发了一种具有快速轴向扫描能力的光学分辨率光声显微镜(OR-PAM)。TAG透镜旨在通过用快速变化的超声驻波调制其屈光力来连续改变OR-PAM的焦平面。通过对碳纤维成像展示了其性能。我们实现了约750μm的景深。还对斑马鱼的头部进行了成像,以进一步证明我们方法的可行性。

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