比较早产和足月等效年龄的磁共振成像用于评估早产脑损伤
Comparison of preterm and term equivalent age MRI for the evaluation of preterm brain injury.
作者信息
Malhotra A, Fahey M C, Davies-Tuck M, Wong F, Carse E, Whiteley G, Ditchfield M
机构信息
Monash Newborn, Monash Children's Hospital, Melbourne, Victoria, Australia.
The Ritchie Centre, Hudson Institute of Medical Research, Melbourne, Victoria, Australia.
出版信息
J Perinatol. 2017 Jul;37(7):864-868. doi: 10.1038/jp.2017.39. Epub 2017 Apr 6.
OBJECTIVE
To compare information obtained from preterm magnetic resonance imaging (MRI; 31-34 weeks) brain scan to that done at term equivalent age.
STUDY DESIGN
Prospective observational study of premature infants with evidence or suspicion of parenchymal brain injury on cranial ultrasound. Brain injury on two scans scored using a scoring system and analyzed.
RESULTS
Fourteen infants with a median (range) gestation at birth of 28 (25-29) weeks and birth weight of 1254 (680-1557) grams were studied. There was a strong correlation between the brain injury scores for the two scans (Spearman ρ=0.87, P=0.001) with excellent agreement between two radiologists (interclass correlation coefficient 0.9-0.94). There was also a high level of agreement between the preterm and term MRI two scores (Intraclass correlation coefficient, 0.79 (0.53-0.94)).
CONCLUSIONS
Preterm MRI is a feasible option for the assessment of preterm brain injury and analysis of data obtained from scan at preterm age is comparable to that obtained at term equivalent age.
目的
比较从早产磁共振成像（MRI；31 - 34周）脑部扫描获得的信息与足月等效年龄时脑部扫描获得的信息。
研究设计
对经头颅超声检查有实质脑损伤证据或怀疑有实质脑损伤的早产儿进行前瞻性观察研究。使用评分系统对两次扫描的脑损伤进行评分并分析。
结果
研究了14例出生时中位（范围）孕周为28（25 - 29）周、出生体重为1254（680 - 1557）克的婴儿。两次扫描的脑损伤评分之间存在强相关性（斯皮尔曼ρ = 0.87，P = 0.001），两名放射科医生之间的一致性良好（组内相关系数0.9 - 0.94）。早产和足月MRI的两个评分之间也有高度一致性（组内相关系数，0.79（0.53 - 0.94））。
结论
早产MRI是评估早产脑损伤的可行选择，早产时扫描获得的数据与足月等效年龄时获得的数据具有可比性。
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