Sidra Medical and Research Center, Translational Medicine, Qatar Foundation, P.O. Box 26999, Doha, Qatar.
Qatar Biomedical Research Institute, Hamad Bin Khalifa University, Qatar Foundation, P.O. Box 5825, Doha, Qatar.
Diabetes Res Clin Pract. 2017 May;127:172-180. doi: 10.1016/j.diabres.2017.03.001. Epub 2017 Mar 22.
Although type 1 diabetes (T1D) is a common disease in the Arab nations, there is no data available on the prevalence of peripheral neuropathy (PN) among T1D subjects in Arab countries. The aim of this study is to analyze the prevalence of PN in T1D subjects via published literature and to draw attention to the dearth of the published work in this serious complication of T1D.
A meta-analysis was performed on studies representing different Arab countries with a total number of 2243 T1D subjects.
The pooled prevalence of PN among T1D subjects in the Arab region was estimated as 18% with 95% confidence intervals (CI): 0.09-0.34. The PN prevalence was significantly higher in the >16-yr age group, with 59.1% (95% CI: 0.45-0.72) compared to 9.5% (95% CI: 0.05-0.19) in the <16-yr age group. Furthermore, the PN prevalence was significantly higher in the group with more than 10-yr T1D, 35% (95% CI: 0.15-0.62) than in the group with less than 10-yr T1D, 9.4% (95% CI: 0.04-0.21).
In Arab countries, PN is common in adults and children with T1D, but prevalence varies widely. Older age Arab people (>16years) with T1D are affected more with PN than younger age Arab people (<16years). PN is more frequently present in Arab subjects with a longer duration of T1D diabetes than in those with shorter duration.
尽管 1 型糖尿病（T1D）在阿拉伯国家是一种常见疾病，但目前尚无关于阿拉伯国家 T1D 患者周围神经病变（PN）患病率的数据。本研究旨在通过已发表的文献分析 T1D 患者中 PN 的患病率，并提请注意在 T1D 这一严重并发症的发表工作中存在的不足。
对代表不同阿拉伯国家的研究进行了荟萃分析，这些研究共有 2243 例 T1D 患者。
阿拉伯地区 T1D 患者中 PN 的总患病率估计为 18%，95%置信区间（CI）为 0.09-0.34。年龄>16 岁的患者中 PN 的患病率明显更高，为 59.1%（95%CI：0.45-0.72），而年龄<16 岁的患者中 PN 的患病率为 9.5%（95%CI：0.05-0.19）。此外，病程超过 10 年的 T1D 患者中 PN 的患病率明显更高，为 35%（95%CI：0.15-0.62），而病程小于 10 年的 T1D 患者中 PN 的患病率为 9.4%（95%CI：0.04-0.21）。
在阿拉伯国家，T1D 成人和儿童中 PN 很常见，但患病率差异很大。年龄较大的阿拉伯人（>16 岁）比年龄较小的阿拉伯人（<16 岁）更容易受到 T1D 的影响。PN 在病程较长的阿拉伯 T1D 患者中比病程较短的患者中更为常见。
