Research Center for Biotechnology, Indonesian Institute of Sciences, Jl. Raya Jakarta-Bogor KM 46 Cibinong, Bogor, West Java 16911, Indonesia.
Molecules. 2021 Mar 27;26(7):1898. doi: 10.3390/molecules26071898.
Marine invertebrates have been reported to be an excellent resource of many novel bioactive compounds. Studies reported that Indonesia has remarkable yet underexplored marine natural products, with a high chemical diversity and a broad spectrum of biological activities. This review discusses recent updates on the exploration of marine natural products from Indonesian marine invertebrates (i.e., sponges, tunicates, and soft corals) throughout 2007-2020. This paper summarizes the structural diversity and biological function of the bioactive compounds isolated from Indonesian marine invertebrates as antimicrobial, antifungal, anticancer, and antiviral, while also presenting the opportunity for further investigation of novel compounds derived from Indonesian marine invertebrates.
海洋无脊椎动物已被证实是许多新型生物活性化合物的重要资源。有研究报道称，印度尼西亚拥有大量尚未开发的海洋天然产物，这些产物具有很高的化学多样性和广泛的生物活性。本文综述了 2007 年至 2020 年期间，从印度尼西亚海洋无脊椎动物（如海绵、被囊动物和软珊瑚）中探索海洋天然产物的最新进展。本文总结了从印度尼西亚海洋无脊椎动物中分离得到的具有抗菌、抗真菌、抗癌和抗病毒活性的生物活性化合物的结构多样性和生物功能，同时也提出了进一步研究印度尼西亚海洋无脊椎动物来源的新型化合物的机会。
