Toppozada H
J Laryngol Otol. 1988 Apr;102(4):314-8.
Ten menopausal females were studied. Histopathologically, the nasal mucosa was normal, except for the tunical glands which were reduced in number, more localized and showed hyperfunction. Histochemically, there was an increased activity of succinic dehydrogenase, alpha esterase, acid and alkaline phosphatase and choline esterase, indicating an increase in carbohydrate metabolism, lipid breakdown, phagocytic activity, vascularity, secretory activity and parasympathetic hyperactivity which may be responsible for these changes, reflecting the emotional disturbances common in the menopause. These changes were not related to the ovarian steroid hormones. The change in the PAS stain was due to the low estrogen blood level.
对10名绝经后女性进行了研究。组织病理学检查显示，除了腺管数量减少、分布更局限且功能亢进外，鼻黏膜正常。组织化学检查发现，琥珀酸脱氢酶、α酯酶、酸性和碱性磷酸酶以及胆碱酯酶的活性增加，表明碳水化合物代谢、脂质分解、吞噬活性、血管生成、分泌活性以及副交感神经功能亢进有所增加，这些可能是导致这些变化的原因，反映了绝经期间常见的情绪障碍。这些变化与卵巢甾体激素无关。PAS染色的变化是由于血液中雌激素水平较低所致。
