Maganga Gael Darren, Abessolo Ndong Andre Lea, Mikala Okouyi Clency Sylde, Makiala Mandanda Sheila, N'Dilimabaka Nadine, Pinto Anais, Agossou Ernest, Cossic Brieuc, Akue Jean-Paul, Leroy Eric Maurice
1 Centre International de Recherches Médicales de Franceville (CIRMF) , Franceville, Gabon .
2 Institut National Supérieur d'Agronomie et de Biotechnologies (INSAB) , Franceville, Gabon .
Vector Borne Zoonotic Dis. 2017 Jun;17(6):443-446. doi: 10.1089/vbz.2016.2065. Epub 2017 Apr 7.
Rift Valley fever (RVF) is a zoonotic disease, which caused several epidemics in humans in many countries of Africa. Using an inhibition enzyme-linked immunosorbent assay (ELISA), real-time reverse transcription PCR, and nested one-step reverse transcription PCR, we conducted a cross-sectional study in populations of sheep and goats from the Mongo County in 2014 to determine the circulation of the Rift Valley fever virus (RVFV) in small ruminants from this area. From a total of 201 small ruminants (95 sheep and 106 goats), the overall IgG seroprevalence against the RVFV was 6.47% (13/201). No RVFV RNA was detected in the animal plasmas. Logistic regression analysis showed that age, species, sex, and locality were not the significant risk factors. The findings of this study highlight the risk of RVF for domestic ruminants bred in this region and for the human rural population living in contact with these animals and they emphasize the need to develop adequate control measures to limit this threat.
裂谷热（RVF）是一种人畜共患病，在非洲许多国家曾引发多起人类疫情。2014年，我们采用抑制性酶联免疫吸附测定（ELISA）、实时逆转录PCR和巢式一步逆转录PCR技术，对来自蒙戈县的绵羊和山羊群体进行了一项横断面研究，以确定该地区小型反刍动物中裂谷热病毒（RVFV）的传播情况。在总共201只小型反刍动物（95只绵羊和106只山羊）中，针对RVFV的总体IgG血清阳性率为6.47%（13/201）。在动物血浆中未检测到RVFV RNA。逻辑回归分析表明，年龄、物种、性别和地理位置不是显著的风险因素。本研究结果凸显了裂谷热对该地区饲养的家养反刍动物以及与这些动物接触的农村人口的风险，并强调需要制定适当的控制措施来限制这一威胁。
