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口腔癌诊断至治疗的时间间隔对生存的影响：一项全国性队列研究。

Influence of time interval from diagnosis to treatment on survival for oral cavity cancer: A nationwide cohort study.

作者信息

Tsai Wen-Chen, Kung Pei-Tseng, Wang Yueh-Hsin, Huang Kuang-Hua, Liu Shih-An

机构信息

Department of Health Services Administration, China Medical University, Taichung, Taiwan.

Department of Healthcare Administration, Asia University, Taichung, Taiwan.

出版信息

PLoS One. 2017 Apr 7;12(4):e0175148. doi: 10.1371/journal.pone.0175148. eCollection 2017.

DOI:10.1371/journal.pone.0175148
PMID:28388649
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5384671/
Abstract

OBJECTIVES

We aimed to explore the relationship between the time interval from diagnosis to treatment and survival of oral cavity squamous cell carcinoma patients.

MATERIALS AND METHODS

A population-based study was conducted between 2004 and 2010. Claims data of oral squamous cell carcinoma patients were retrieved from the Taiwan Cancer Registry Database. Secondary data were obtained from Taiwan's National Health Insurance Research Database.

RESULTS

A total of 21,263 patients were included in the final analysis. The majority of the patients received treatment within 30 days of diagnosis (n = 18,193, 85.5%), while 572 patients (2.7%) underwent treatment after 120 days. The patients who were treated after 120 days had a higher risk of death when compared to those treated within 30 days (Hazard ratio: 1.32, 95% Confidence intervals: 1.19 to 1.47).

CONCLUSION

A longer time interval from diagnosis to treatment was found to be associated with a poorer prognosis among patients suffering from oral squamous cell carcinoma.

摘要

目的

我们旨在探讨口腔鳞状细胞癌患者从诊断到治疗的时间间隔与生存率之间的关系。

材料与方法

在2004年至2010年间进行了一项基于人群的研究。口腔鳞状细胞癌患者的理赔数据取自台湾癌症登记数据库。二级数据来自台湾全民健康保险研究数据库。

结果

共有21263名患者纳入最终分析。大多数患者在诊断后30天内接受了治疗（n = 18193，85.5%），而572名患者（2.7%）在120天后接受了治疗。与在30天内接受治疗的患者相比，120天后接受治疗的患者死亡风险更高（风险比：1.32，95%置信区间：1.19至1.47）。

结论

发现口腔鳞状细胞癌患者从诊断到治疗的时间间隔较长与预后较差有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36c4/5384671/5122b4b909f9/pone.0175148.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36c4/5384671/29feac41962a/pone.0175148.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36c4/5384671/5122b4b909f9/pone.0175148.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36c4/5384671/29feac41962a/pone.0175148.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/36c4/5384671/5122b4b909f9/pone.0175148.g002.jpg

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