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2012 - 2016年发表的医疗保健干预措施综述的流行病学及报告特征:一项系统综述方案

Epidemiology and reporting characteristics of overviews of reviews of healthcare interventions published 2012-2016: protocol for a systematic review.

作者信息

Pieper Dawid, Pollock Michelle, Fernandes Ricardo M, Büchter Roland Brian, Hartling Lisa

机构信息

Institute for Research in Operative Medicine, Witten/Herdecke University, Ostmerheimer Str. 200, Building 38, 51109, Cologne, Germany.

Alberta Research Centre for Health Evidence, Department of Pediatrics, University of Alberta, Edmonton, Canada.

出版信息

Syst Rev. 2017 Apr 7;6(1):73. doi: 10.1186/s13643-017-0468-9.

DOI:10.1186/s13643-017-0468-9
PMID:28388960
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5383951/
Abstract

BACKGROUND

Overviews of systematic reviews (overviews) attempt to systematically retrieve and summarize the results of multiple systematic reviews (SRs) for a given condition or public health problem. Two prior descriptive analyses of overviews found substantial variation in the methodological approaches used in overviews, and deficiencies in reporting of key methodological steps. Since then, new methods have been developed so it is timely to update the prior descriptive analyses. The objectives are to: (1) investigate the epidemiological, descriptive, and reporting characteristics of a random sample of 100 overviews published from 2012 to 2016 and (2) compare these recently published overviews (2012-2016) to those published prior to 2012 (based on the prior descriptive analyses).

METHODS

Medline, EMBASE, and CDSR will be searched for overviews published 2012-2016, using a validated search filter for overviews. Only overviews written in English will be included. All titles and abstracts will be screened by one review author; those deemed not relevant will be verified by a second person for exclusion. Full-texts will be assessed for inclusion by two reviewers independently. Of those deemed relevant, a random sample of 100 overviews will be selected for inclusion. Data extraction will be either performed by one reviewer with verification by a second reviewer or by one reviewer only depending on the complexity of the item. Discrepancies at any stage will be resolved by consensus or consulting a third person. Data will be extracted on the epidemiological, descriptive, and reporting characteristics of each overview. Data will be analyzed descriptively. When data are available for both time points (up to 2011 vs. 2012-2016), we will compare characteristics by calculating risk ratios or applying the Mann-Whitney test.

DISCUSSION

Overviews are becoming increasingly valuable evidence syntheses, and the number of published overviews is increasing. However, former analyses found limitations in the conduct and reporting of overviews. This update of a recent sample of overviews will inform whether this has changed, while also identifying areas for further improvement.

SYSTEMATIC REVIEW REGISTRATION

The review will not be registered in PROSPERO as it does not meet the eligibility criterion of dealing with health-related outcomes.

摘要

背景

系统评价概述(概述)试图系统地检索和总结针对特定疾病或公共卫生问题的多个系统评价(SR)的结果。之前对概述的两项描述性分析发现,概述中使用的方法学方法存在很大差异,关键方法学步骤的报告也存在缺陷。从那时起,已经开发了新的方法,因此及时更新之前的描述性分析是很有必要的。目标是:(1)调查2012年至2016年发表的100篇随机抽样概述的流行病学、描述性和报告特征;(2)将这些最近发表的概述(2012 - 2016年)与2012年之前发表的概述(基于之前的描述性分析)进行比较。

方法

将检索Medline、EMBASE和CDSR中2012年至2016年发表的概述,使用经过验证的概述检索过滤器。仅纳入英文撰写的概述。所有标题和摘要将由一名综述作者进行筛选;那些被认为不相关的将由第二人进行核实以排除。全文将由两名审稿人独立评估是否纳入。在那些被认为相关的概述中,将随机抽取100篇纳入。数据提取将由一名审稿人进行,第二名审稿人进行核实,或者仅由一名审稿人进行,具体取决于项目的复杂性。任何阶段的差异将通过协商一致或咨询第三人来解决。将提取关于每个概述的流行病学、描述性和报告特征的数据。将对数据进行描述性分析。当两个时间点(截至2011年与2012 - 2016年)都有数据时,我们将通过计算风险比或应用曼 - 惠特尼检验来比较特征。

讨论

概述正成为越来越有价值的证据综合,并且发表的概述数量在增加。然而,之前的分析发现概述在开展和报告方面存在局限性。对最近一批概述样本的此次更新将说明这种情况是否已发生变化,同时也确定进一步改进的领域。

系统评价注册

该评价不会在PROSPERO中注册,因为它不符合处理与健康相关结果的资格标准。

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