西班牙裔和白人之间早发性和迟发性结直肠癌发病率的差异：一项 SEER 数据库 10 年研究。
Disparities in incidence of early- and late-onset colorectal cancer between Hispanics and Whites: A 10-year SEER database study.
机构信息
UA Department of Surgery, Division of Surgical Oncology, 1501 N Campbell Avenue, Tucson, AZ 85724, USA.
UA Department of Surgery, Division of Surgical Oncology, 1501 N Campbell Avenue, Tucson, AZ 85724, USA.
出版信息
Am J Surg. 2018 Apr;215(4):581-585. doi: 10.1016/j.amjsurg.2017.03.035. Epub 2017 Mar 31.
BACKGROUND
Racial disparities in incidence of colorectal cancer (CRC) exist. In Hispanics, CRC was the second most commonly diagnosed cancer in 2012.
METHODS
We abstracted the national estimates for Hispanics/Whites with CRC using the SEER database between 2000 and 2010. Trends in incidence, mortality, gender and stage of disease were analyzed for early-onset (age<50; EO - young) and late-onset (age>50; LO - old) cases.
RESULTS
The overall incidence of CRC increased by 48% in Hispanics. 38% increase in incidence of LO CRC and 80% increase in incidence of EO CRC was seen in this ethnic group. Hispanics and Whites showed higher percentage of distant tumors for both age groups. There was no deviation in overall trend between males and females.
CONCLUSIONS
Although there is an overall decrease in incidence of CRC in Whites increase was seen in Hispanics. While incidence of EO CRC is increasing in both races, LO CRC incidence is increasing in Hispanics not in Whites. This data suggest that disparities in incidence of EO and LO CRC exist between Hispanics and Whites.
背景
结直肠癌（CRC）的发病率存在种族差异。在西班牙裔中，CRC 是 2012 年第二大常见癌症。
方法
我们使用 SEER 数据库，从 2000 年到 2010 年，对西班牙裔/白种人 CRC 患者的国家估计值进行了摘要。分析了早发（年龄<50；EO-年轻）和晚发（年龄>50；LO-老年）病例的发病率、死亡率、性别和疾病分期的趋势。
结果
西班牙裔 CRC 的总体发病率增加了 48%。在该族裔中，LO CRC 的发病率增加了 38%，EO CRC 的发病率增加了 80%。西班牙裔和白种人在两个年龄组中都有更高比例的远处肿瘤。男女之间的总体趋势没有偏差。
结论
尽管白种人 CRC 的总体发病率有所下降，但西班牙裔的发病率却有所上升。虽然两个种族的 EO CRC 发病率都在增加，但 LO CRC 的发病率仅在西班牙裔中增加，而不是在白种人中增加。这些数据表明，西班牙裔和白种人之间存在 EO 和 LO CRC 发病率的差异。
Zotero 插件