Keshavarzi Maryam, Darijani Mansoreh, Momeni Fatemeh, Moradi Pouya, Ebrahimnejad Hamed, Masoudifar Aria, Mirzaei Hamed
Department of Oral and Maxillofacial Radiology, School of Dentistry, Lorestan University of Medical Sciences, Khorramabad, Iran.
Department of Oral and Maxillofacial Radiology, School of Dentistry, Kerman University of Medical Sciences, Kerman, Iran.
J Cell Biochem. 2017 Oct;118(10):3055-3060. doi: 10.1002/jcb.26042. Epub 2017 May 23.
Oral cancer is known as one of relatively common type of cancer worldwide. Despite the easy access of the oral cavity to examination, oral tumors are diagnosed in more advanced stages of the disease. Imaging techniques have been recently emerged as non-invasive approaches to detect molecular and cellular changes in living cells and organisms. These techniques such as computed tomography (CT), magnetic resonance imaging (MRI), and positron emission tomography (PET) could help physicians to screen patients with oral tumors particularly oral squamous cell carcinoma (OSCC) in early stage of the disease. In this review, we discuss that early detection and diagnosis of oral tumors through using more robust and precise imaging techniques and a variety of cellular/molecular biomarkers not only could lead to more effective and less aggressive form of treatment for the disease but also could improve survival rates and lower treatment costs. J. Cell. Biochem. 118: 3055-3060, 2017. © 2017 Wiley Periodicals, Inc.
口腔癌是全球范围内相对常见的癌症类型之一。尽管口腔易于检查，但口腔肿瘤往往在疾病的更晚期才被诊断出来。成像技术最近已成为检测活细胞和生物体中分子和细胞变化的非侵入性方法。诸如计算机断层扫描（CT）、磁共振成像（MRI）和正电子发射断层扫描（PET）等技术可以帮助医生在疾病早期筛查口腔肿瘤患者，尤其是口腔鳞状细胞癌（OSCC）患者。在本综述中，我们讨论了通过使用更强大、更精确的成像技术和各种细胞/分子生物标志物来早期检测和诊断口腔肿瘤，这不仅可以导致对该疾病更有效、侵袭性更小的治疗形式，还可以提高生存率并降低治疗成本。《细胞生物化学杂志》118: 3055 - 3060, 2017。© 2017威利期刊公司。
