Mery Benoîte, Guichard Jean-Baptiste, Guy Jean-Baptiste, Vallard Alexis, Barthelemy Jean-Claude, Da Costa Antoine, Magné Nicolas, Bertoletti Laurent
Department of Medical Oncology, Lucien Neuwirth Cancer Institute, St Priest en Jarez, France.
Division of Cardiology, Jean Monnet University, Saint-Etienne, France.
Int J Cardiol. 2017 Aug 1;240:196-202. doi: 10.1016/j.ijcard.2017.03.132. Epub 2017 Apr 6.
An increase of atrial fibrillation (AF) incidence in cancer patients has recently been pointed out, with complex interrelationships between these two entities on top of surgery factors. Most of present knowledge comes from retrospective studies or data from registries but the underlying mechanisms of the association between atrial fibrillation and cancer are still unclear. An increased risk of AF in cancer patients could represent a major public health problem although scarce information is available for the challenging management of such patients with distinctive features, especially in terms of antithrombotic therapy. Elaborate evidence-based approaches are thus required. This review provides an insight into AF among cancer patients through an overview of the underlying mechanisms, epidemiology evidence and future therapeutic challenges.
最近有研究指出，癌症患者心房颤动（AF）的发病率有所上升，除手术因素外，这两种疾病之间还存在复杂的相互关系。目前的大部分知识来自回顾性研究或登记数据，但心房颤动与癌症之间关联的潜在机制仍不清楚。癌症患者发生AF的风险增加可能是一个重大的公共卫生问题，尽管对于这类具有独特特征患者的挑战性管理，尤其是在抗血栓治疗方面，可用信息很少。因此，需要精心制定基于证据的方法。本综述通过概述潜在机制、流行病学证据和未来治疗挑战，深入探讨了癌症患者中的AF。
