Medysky Mary E, Temesi John, Culos-Reed Susan Nicole, Millet Guillaume Y
Human Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, Canada.
Human Performance Laboratory, Faculty of Kinesiology, University of Calgary, Calgary, Canada; Department of Oncology, Cumming School of Medicine, Calgary, Canada; Department of Psychosocial Resources, Tom Baker Cancer Centre, Calgary, Canada.
Neurophysiol Clin. 2017 Apr;47(2):111-122. doi: 10.1016/j.neucli.2017.03.001. Epub 2017 Apr 5.
Cancer-related fatigue (CRF) is a commonly reported and debilitating side effect of cancer and/or cancer treatment. Sleep disorders are also highly reported in the cancer population; however it is unknown if sleep is associated with fatigue. In the general population, exercise has been shown to improve sleep, however in the cancer population this idea is under investigation. The primary purposes of this review were to: (i) review the prevalence and causes of sleep disorders in cancer patients and survivors, (ii) examine the relationship between sleep and CRF and (iii) review the impact of exercise interventions on sleep in cancer patients and survivors. A scoping review of the literature was conducted regarding exercise interventions in cancer patients and survivors with sleep as at least one outcome measure. A search of the literature revealed limited studies (n=21) assessing the effect of exercise on sleep disorders in the cancer population. Methodological issues are evident because assessing sleep is often not the main outcome of interest. The reviewed studies revealed that exercise positively impacts sleep quality and quantity. There seems to be possible relationship between sleep disorders, exercise and CRF. Further investigation of this relationship is necessary, specifically using objective measurement tools, in large, controlled studies, focusing on sleep as the primary outcome.
癌症相关疲劳(CRF)是癌症和/或癌症治疗中常见且使人衰弱的副作用。睡眠障碍在癌症患者群体中也有很高的发生率;然而,睡眠是否与疲劳相关尚不清楚。在一般人群中,运动已被证明可改善睡眠,但在癌症患者群体中,这一观点仍在研究中。本综述的主要目的是:(i)回顾癌症患者和幸存者睡眠障碍的患病率及原因,(ii)研究睡眠与CRF之间的关系,以及(iii)回顾运动干预对癌症患者和幸存者睡眠的影响。针对以睡眠作为至少一项结局指标的癌症患者和幸存者运动干预进行了文献综述。文献检索发现评估运动对癌症患者群体睡眠障碍影响的研究有限(n = 21)。方法学问题很明显,因为评估睡眠往往不是主要关注的结局。综述的研究表明,运动对睡眠质量和时长有积极影响。睡眠障碍、运动和CRF之间似乎存在可能的关系。有必要在大型对照研究中进一步研究这种关系,特别是使用客观测量工具,将睡眠作为主要结局。