Vaccaro Roberta, Borrelli Paola, Abbondanza Simona, Davin Annalisa, Polito Letizia, Colombo Mauro, Francesca Vitali Silvia, Villani Simona, Guaita Antonio
"Golgi Cenci" Foundation, Corso San Martino 10, 20081 Abbiategrasso, Italy; "C. Golgi" Geriatric Institute, Piazza Samek 5, 20081 Abbiategrasso, Italy.
Unit of Biostatistics and Clinical Epidemiology, Department of Public Health, Experimental and Forensic Medicine, University of Pavia, Via Forlanini 2, 27100 Pavia, Italy.
Biomed Res Int. 2017;2017:3592359. doi: 10.1155/2017/3592359. Epub 2017 Mar 14.
Estimates of depressive disorders in the elderly vary depending on how cases are defined. We estimated the prevalence of subthreshold depression (SD) and clinically significant depression (D) in a population of 70-74-year-olds. We also looked for associations with sociodemographic factors and perceptions of self. Participants underwent a multidimensional assessment (social, medical, and neuropsychological). The estimated prevalence of SD was 15.71% (95% CI: 13.70-17.72), while that of D was 5.58% (95% CI: 4.31-6.85). Multinomial logistic regression analysis revealed that female gender and dissatisfaction with family relationships were related to SD and D. A self-perception of physical age as older than actual age (but not comorbidity) and greater self-perceived stress caused by negative life events both increased the probability of SD. The likelihood of D was decreased in those who perceived their own health as good, whereas a self-perception of mental age as older than actual age and dissatisfaction with relationships with friends were both significantly associated with D. Both SD and D emerged as key problems in our population. Female gender and self-perceptions of various characteristics, which can be explored through simple questions, are associated with late-life depression in elderly people independently of their actual physical condition and other characteristics.
老年人抑郁症的估计数因病例定义方式而异。我们估计了70 - 74岁人群中亚阈下抑郁(SD)和具有临床意义的抑郁症(D)的患病率。我们还研究了其与社会人口学因素及自我认知之间的关联。参与者接受了多维度评估(社会、医学和神经心理学方面)。SD的估计患病率为15.71%(95%置信区间:13.70 - 17.72),而D的患病率为5.58%(95%置信区间:4.31 - 6.85)。多项逻辑回归分析显示,女性以及对家庭关系不满意与SD和D相关。自我感觉生理年龄比实际年龄大(而非合并症)以及负面生活事件导致的更大自我感知压力均增加了患SD的概率。那些认为自己健康状况良好的人患D的可能性降低,而自我感觉心理年龄比实际年龄大以及对朋友关系不满意均与D显著相关。SD和D在我们的研究人群中均成为关键问题。女性以及通过简单问题即可探究的各种特征的自我认知,独立于其实际身体状况和其他特征,与老年人晚年抑郁症相关。