Frehner Florian, Benthien Jan P
1 University of Basel, Basel, Switzerland.
Cartilage. 2018 Oct;9(4):339-345. doi: 10.1177/1947603517700956. Epub 2017 Apr 10.
Objective This study is a literature review from 2010 to 2014 concerning the quality of evidence in clinical trials about microfracture in attempt to repair articular cartilage. We have decided to focus on microfracturing, since this seems to be the best documented technique. Interest in evaluation of publication quality has risen in orthopaedic sports medicine recently. Therefore, we think it is necessary to evaluate recent clinical trials being rated for their evidence-based medicine (EBM) quality. We also compared the mean impact factor of the journals publishing the different studies as an indicator of the study's citation and evaluated for a change over the studied time frame. Design To measure the EBM level, we applied the modified Coleman Methodology Score (CMS) introduced by Jakobsen. The impact factor, which is a measurement of the yearly average number of citations of articles recently published in that journal, was evaluated according to self-reported values on the corresponding journal's website. Results We found that the mean CMS has not changed between 2010 and 2014. The mean impact factor has also not changed between 2010 and 2014. The CMS variance was high, pointing to different qualities in the evaluated studies. There is no evidence that microfracturing is superior compared to other cartilage repair procedures. Conclusion Microfracture cannot be seen as an evidence based procedure. Further research needs to be done and a standardization of the operating method is desirable. There need to be more substantial studies on microfracturing alone without additional therapies.
目的 本研究是一项关于2010年至2014年期间尝试修复关节软骨的微骨折临床试验证据质量的文献综述。我们决定聚焦于微骨折技术,因为这似乎是记录最为详尽的技术。近来,骨科运动医学领域对出版物质量评估的关注度有所提高。因此,我们认为有必要对近期被评定为循证医学(EBM)质量的临床试验进行评估。我们还比较了发表不同研究的期刊的平均影响因子,以此作为研究被引用情况的指标,并评估在所研究的时间范围内的变化情况。
设计 为衡量EBM水平,我们应用了雅各布森引入的改良科尔曼方法评分(CMS)。影响因子是该期刊近期发表文章的年平均被引用次数的衡量指标,根据相应期刊网站上的自我报告值进行评估。
结果 我们发现2010年至2014年期间平均CMS没有变化。2010年至2014年期间平均影响因子也没有变化。CMS的方差很大,表明所评估研究的质量存在差异。没有证据表明微骨折技术比其他软骨修复手术更具优势。
结论 微骨折技术不能被视为基于证据的手术方法。需要进一步开展研究,并且手术方法的标准化是可取的。需要开展更多仅针对微骨折技术而无其他附加治疗的实质性研究。