阿奇霉素（CP 62,993）、克拉霉素（A - 56268；TE - 031）、红霉素、罗红霉素及克林霉素的体外活性
In vitro activities of azithromycin (CP 62,993), clarithromycin (A-56268; TE-031), erythromycin, roxithromycin, and clindamycin.
作者信息
Barry A L, Jones R N, Thornsberry C
机构信息
Clinical Microbiology Institute, Tualatin, Oregon 97062.
出版信息
Antimicrob Agents Chemother. 1988 May;32(5):752-4. doi: 10.1128/AAC.32.5.752.
Abstract
The in vitro activity of azithromycin (CP 62,993 or XZ-450) against Haemophilus influenzae was greater than that of three other macrolides. However, azithromycin was four- to eightfold less active than erythromycin against the gram-positive cocci and against Listeria monocytogenes. Erythromycin and azithromycin were similar in their activity against Legionella pneumophila, Neisseria gonorrhoeae, Neisseria meningitidis, and Branhamella catarrhalis.
摘要
阿奇霉素（CP 62,993或XZ - 450）对流感嗜血杆菌的体外活性高于其他三种大环内酯类药物。然而，阿奇霉素对革兰氏阳性球菌和单核细胞增生李斯特菌的活性比对红霉素低4至8倍。红霉素和阿奇霉素对嗜肺军团菌、淋病奈瑟菌、脑膜炎奈瑟菌和卡他莫拉菌的活性相似。
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