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SF-36量表对预测腹腔镜治疗轻度子宫内膜异位症后生活质量改善情况的术前相关性。

SF-36 preoperative interest of predicting improvement of quality of life after laparoscopic management of minimal endometriosis.

作者信息

Valentin L, Canis M, Pouly J-L, Lasnier C, Jaffeux P, Aublet-Cuvelier B, Bourdel N

机构信息

Department of gynecologic surgery, CHU Caen, avenue Côte-de-Nacre, 14033 Caen cedex 9, France.

Department of gynecologic surgery, CHU Estaing Clermont-Ferrand, 63058 Clermont-Ferrand cedex1, France; Clermont university, université d'Auvergne, ISIT UMR6284, 28, place Henri-Dunant, BP 10448, 63000 Clermont-Ferrand, France.

出版信息

J Gynecol Obstet Hum Reprod. 2017 Feb;46(2):137-142. doi: 10.1016/j.jogoh.2016.12.004. Epub 2017 Jan 30.

DOI:10.1016/j.jogoh.2016.12.004
PMID:28403969
Abstract

THE PURPOSE OF THE STUDY

To study preoperative thresholds of the SF-36 components above which we can predict a high risk of failure in order to improve the quality of life after surgery for patients with minimal endometriosis.

MATERIAL AND METHODS

Design: prospective and multicenter observational study between February 2004 and 2011.

PATIENTS

167 patients with operated minimal endometriosis.

SETTING

for the Physical Component Summary (PCS) or the Mental Component Summary (MCS) subscales of the SF-36 questionnaire, an improvement defined by an increase of 5 points.

INTERVENTION

evaluation by the SF-36 questionnaire the week before and one year after surgery.

MEASUREMENT AND MAIN RESULTS

Success of surgery measured by an improvement in both components. We found significantly different initial variables between patients with improvement and those without: initial MCS score (P=0.0003), initial PCS score (P<0.0001) and dyspareunia (P=0.004). Multivariate analysis revealed only two significant variables. Initial MCS higher than 40 (OR=4.6) and initial PCS higher than 50 (OR=10.6) are risk factors for failure of improvement after surgery.

CONCLUSION

Surgery is seldom a good treatment for improving QOL in minimal endometriosis. We set two thresholds for SF-36, 50 for PCS and 40 for MCS: above there is a very high risk of failure (86% of failure in our population). Under, the risk of failure remains high (54.3%).

CANADIAN TASK FORCE CLASSIFICATION OF STUDY DESIGN

Evidence obtained from well-designed cohort or case-control studies, preferably from more than one center or research group.

摘要

研究目的

研究SF-36各维度的术前阈值,超过该阈值我们就能预测高失败风险,以便改善轻度子宫内膜异位症患者术后的生活质量。

材料与方法

设计:2004年2月至2011年期间的前瞻性多中心观察性研究。

患者

167例接受手术治疗的轻度子宫内膜异位症患者。

设置

对于SF-36问卷的身体成分总结(PCS)或心理成分总结(MCS)子量表,改善定义为增加5分。

干预

在手术前一周和术后一年通过SF-36问卷进行评估。

测量与主要结果

通过两个维度的改善来衡量手术的成功。我们发现改善组和未改善组患者之间的初始变量存在显著差异:初始MCS评分(P = 0.0003)、初始PCS评分(P < 0.0001)和性交困难(P = 0.004)。多变量分析仅显示两个显著变量。初始MCS高于40(OR = 4.6)和初始PCS高于50(OR = 10.6)是术后改善失败的危险因素。

结论

手术很少是改善轻度子宫内膜异位症患者生活质量的良好治疗方法。我们为SF-36设定了两个阈值,PCS为50,MCS为40:高于此值,失败风险非常高(在我们的研究人群中失败率为86%)。低于此值,失败风险仍然很高(54.3%)。

加拿大工作组对研究设计的分类

从精心设计的队列研究或病例对照研究中获得的证据,最好来自多个中心或研究组。

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