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免疫抑制状态下的水痘性胃炎:1例因肉芽肿性多血管炎行肺移植术后女性患者的病例报告

[Varicella gastritis under immunosuppression : Case report of a woman after lung transplantation due to granulomatosis with polyangiitis].

作者信息

Saman S, Henes J-C, Niepel D, Bosmüller H, Werner C R, Lauer U M, Malek N P, Xenitidis T

机构信息

Abteilung Innere Medizin I (Hepatologie, Gastroenterologie, Infektiologie), Universitätsklinikum Tübingen, Otfried-Müller-Str. 10, 72076, Tübingen, Deutschland.

Abteilung Innere Medizin II (Onkologie, Hämatologie, Rheumatologie, Immunologie, Pulmonologie), Universitätsklinikum Tübingen, Otfried-Müller-Str. 10, 72076, Tübingen, Deutschland.

出版信息

Internist (Berl). 2017 Aug;58(8):855-858. doi: 10.1007/s00108-017-0231-2.

Abstract

A 35-year-old woman who had previously undergone a lung transplantation presented with severe abdominal pain and vomiting. The gastroscopy showed diffuse ulcerative gastric lesions. Tests for varicella zoster virus and Epstein-Barr virus via polymerase chain reactions (PCR) on endoscopically obtained gastric biopsies were found to be positive and confirmed varicella gastritis. Intravenous antiviral therapy with acyclovir was administered resulting in a normalization of all clinical symptoms, especially of abdominal pain and inflammation parameters.

摘要

一名曾接受过肺移植的35岁女性出现严重腹痛和呕吐。胃镜检查显示胃内有弥漫性溃疡性病变。通过聚合酶链反应(PCR)对内镜下获取的胃活检组织进行水痘带状疱疹病毒和EB病毒检测,结果呈阳性,确诊为水痘性胃炎。给予静脉注射阿昔洛韦抗病毒治疗,所有临床症状,尤其是腹痛和炎症指标恢复正常。

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