Sarac G, Kapicioglu Y, Cayli S, Altas A, Yologlu S
Department of Dermatology, Faculty of Medicine, Inonu University, Malatya, Turkey.
Turgut Ozal Medical Center, Malatya, Turkey.
Niger J Clin Pract. 2017 Apr;20(4):474-478. doi: 10.4103/1119-3077.204371.
Psoriasis is a common, chronic, inflammatory, and hyperproliperative skin disease. It has been known that the infectious agents play a role in triggering and exacerbation of the disease. Periodontal diseases are chronic inflammatory gum diseases initiated by microorganisms in dental plaques. This study intended to determine the role of periodontal diseases, as chronic infective foci in psoriasis.
A total of 76 patients, who applied to Faculty of Medicine, Department of Dermatology, İnönü University, diagnosed as psoriasis and a control group consisting of 76 dermatologic patients without any systemic disease at similar age and gender were included the study. The dental examinations of the subjects were done by the Community Periodontal Index of Treatment Needs index system, using a periodontal probe.
Significant difference was identified between the patients with psoriasis and control group, in terms of CPI (Community Periodontal Index), oral hygiene habits, frequency of tooth brushing and flossing (P = 0.01, P = 0.001, P = 0.01, P = 0.05, respectively). A positive correlation between the severities of psoriasis and dental disease was determined, but this difference was not statistically significant (P = 0.204).
The periodontal disease may affect psoriasis as a chronic infectious focus and probably through proinflammatory cytokines. In order to clarify the exact role of periodontal disease in psoriasis, the issue should be studied in larger series with serum cytokine levels.
银屑病是一种常见的慢性炎症性增殖性皮肤病。已知感染因素在该疾病的触发和加重中起作用。牙周病是由牙菌斑中的微生物引发的慢性牙龈炎症性疾病。本研究旨在确定牙周病作为银屑病慢性感染灶的作用。
本研究纳入了76例就诊于伊诺努大学医学院皮肤科并被诊断为银屑病的患者,以及一个由76名年龄和性别相仿且无任何系统性疾病的皮肤科患者组成的对照组。使用牙周探针,通过社区牙周治疗需求指数系统对受试者进行牙科检查。
银屑病患者与对照组在社区牙周指数(CPI)、口腔卫生习惯、刷牙和使用牙线频率方面存在显著差异(分别为P = 0.01、P = 0.001、P = 0.01、P = 0.05)。确定了银屑病严重程度与牙科疾病之间存在正相关,但这种差异无统计学意义(P = 0.204)。
牙周病可能作为慢性感染灶影响银屑病,可能是通过促炎细胞因子。为了阐明牙周病在银屑病中的确切作用,应在更大规模的系列研究中结合血清细胞因子水平对该问题进行研究。