Fan Ming-Yue, Tang Xu, Huang Wei, Dai Hua, Liu Xing-Can, Xia Yin-Yin, Meng Pan, Zhang Rui-Yuan, Guo Yu-Ming, Cheng Shu-Qun
School of Public Health and Management, Chongqing Medical University, Chongqing 400016, China.
Zhongguo Dang Dai Er Ke Za Zhi. 2017 Apr;19(4):436-440. doi: 10.7499/j.issn.1008-8830.2017.04.015.
To investigate the effect of air pollution on respiratory health in school-aged children in the main urban area of Chongqing, China.
The main urban area of Chongqing was divided into polluted area and clean area according to the air pollution data shown on the Environmental Protection Agency Website of Chongqing between 2010 and 2015. A cluster sampling method was used to select 695 third- or fourth-grade children from 2 primary schools in the clean or polluted area as study subjects, with 313 children from the clean area and 382 children from the polluted area. Pulmonary function was examined for all children and a standard American epidemiological questionnaire (ATS-DLD-78-C) was used to investigate the prevalence of respiratory diseases and symptoms.
Compared with the clean area, the polluted area had significantly higher concentrations of inhalable particles (PM), fine particulate matter (PM), and nitric oxide (NO) (P<0.05). The multivariate logistic regression analysis was performed after adjustment for confounding factors, and the results showed that compared with those in the clean area, the children in the polluted area had significantly higher risks of cough (OR=1.644), cough during cold (OR=1.596), expectoration during cold (OR=2.196), persistent expectoration (OR=1.802), and wheezing (OR=2.415). The boys and girls in the clean area had significantly higher forced vital capacity and forced expiratory volume in one second than those in the polluted area (P<0.05).
Air pollution in the main urban area of Chongqing is associated with the increased prevalence of respiratory symptoms in school-aged children and has certain effect on children's pulmonary function.
探讨中国重庆主城区空气污染对学龄儿童呼吸健康的影响。
根据重庆市环境保护局网站2010年至2015年显示的空气污染数据,将重庆主城区分为污染区和清洁区。采用整群抽样方法,从清洁区或污染区的2所小学中选取695名三、四年级儿童作为研究对象,其中清洁区313名儿童,污染区382名儿童。对所有儿童进行肺功能检查,并使用标准的美国流行病学调查问卷(ATS-DLD-78-C)调查呼吸道疾病和症状的患病率。
与清洁区相比,污染区的可吸入颗粒物(PM)、细颗粒物(PM)和一氧化氮(NO)浓度显著更高(P<0.05)。在对混杂因素进行调整后进行多因素逻辑回归分析,结果显示,与清洁区儿童相比,污染区儿童咳嗽(OR=1.644)、感冒时咳嗽(OR=1.596)、感冒时咳痰(OR=2.196)、持续性咳痰(OR=1.802)和喘息(OR=2.415)的风险显著更高。清洁区的男孩和女孩的用力肺活量和一秒用力呼气量显著高于污染区(P<0.05)。
重庆主城区的空气污染与学龄儿童呼吸道症状患病率增加有关,并对儿童肺功能有一定影响。