Goren A, Hellmann S, Gabbay Y, Brenner S
Ministry of the Environment, and Sackler School of Medicine, Tel-Aviv University, Israel.
Arch Environ Health. 1999 May-Jun;54(3):165-71. doi: 10.1080/00039899909602255.
During the spring of 1995, schoolchildren aged 7-13 y who lived in a rural area in Israel were studied. These children lived in two communities: in one community, the population was exposed to pollution from a cement factory and quarries; the population of the second community was not exposed to pollution from these sources. The children from participating schools performed forced vital capacity, forced expiratory volume in 1 s, peak expiratory flow, forced expiratory flow at 50%, and forced expiratory flow at 25%. Parents completed an American Thoracic Society-National Heart and Lung Institute health questionnaire, which included information about respiratory symptoms and diseases of the children and information about background variables. A trend of higher prevalence of most respiratory symptoms occurred in 638 children who were growing up in the community that bordered the industrial zone, compared with 338 children from the unexposed community. Cough without cold, sputum without cold, and cough accompanied by sputum were the most prevalent symptoms. Asthma diagnosed by a physician was reported more frequently for children who lived near the polluting sources. No consistent trend of reduced pulmonary function tests was observed among children who lived in the polluted community; however, peak expiratory flow was significantly lower among these children. Odds ratio values, calculated from logistic regressions in which we controlled for respiratory problems among parents, mothers who smoked, crowding index, education of mothers, and residential heating, were 3.6 (p value for model = .244) for cough without cold, 4.0 (p value for model = .333) for asthma, and 2.2 (p value for model = .753) for asthma and/or bronchitis in the polluted area, compared with 1.0 in the low-pollution community. Total suspended particulate matter and levels of airborne particles less than 10 microns, measured in the community bordering the industrial zone, very often violated the relevant 24-h Israeli standards of 200 microg/m3 and 150 microg/m3, respectively.
1995年春季,对居住在以色列农村地区的7至13岁学童进行了研究。这些孩子生活在两个社区:在一个社区,居民暴露于水泥厂和采石场的污染中;第二个社区的居民未暴露于这些污染源。参与研究的学校的孩子们进行了用力肺活量、1秒用力呼气量、呼气峰值流速、50%用力呼气流量和25%用力呼气流量测试。家长们填写了一份美国胸科学会-国家心肺研究所健康问卷,其中包括有关孩子呼吸道症状和疾病的信息以及背景变量信息。与来自未受污染社区的338名儿童相比,在毗邻工业区的社区中成长的638名儿童中,大多数呼吸道症状的患病率呈上升趋势。无感冒咳嗽、无感冒咳痰以及伴有咳痰的咳嗽是最常见的症状。居住在污染源附近的儿童中,医生诊断出哮喘的情况更为频繁。在居住在污染社区的儿童中,未观察到肺功能测试持续下降的趋势;然而,这些儿童的呼气峰值流速明显较低。在对父母的呼吸道问题、吸烟的母亲、拥挤指数、母亲的教育程度和住宅供暖情况进行控制的逻辑回归分析中,污染地区无感冒咳嗽的比值比为3.6(模型p值 = 0.244),哮喘为4.0(模型p值 = 0.333),哮喘和/或支气管炎为2.2(模型p值 = 0.753),而低污染社区为1.0。在毗邻工业区的社区测量的总悬浮颗粒物和小于10微米的空气颗粒物水平,经常分别违反以色列相关的24小时标准,即200微克/立方米和150微克/立方米。