卵子发生中的不对称分裂。

Asymmetric Divisions in Oogenesis.

作者信息

Bilinski Szczepan M, Kubiak Jacek Z, Kloc Malgorzata

机构信息

Institute of Zoology, Jagiellonian University, Gronostajowa 9, 30-387, Krakow, Poland.

CNRS UMR 6290, Institute of Genetics and Development of Rennes, Cell Cycle Group, IFR 140 GFAS, Faculty of Medicine, University of Rennes 1, 35 043, Rennes, France.

出版信息

Results Probl Cell Differ. 2017;61:211-228. doi: 10.1007/978-3-319-53150-2_9.

DOI:10.1007/978-3-319-53150-2_9

PMID:28409306

Abstract

In the majority of animals, the oocyte/egg is structurally, molecularly, and functionally asymmetric. Such asymmetry is a prerequisite for a flawless fertilization and faithful segregation of maternal determinants during subsequent embryonic development. The oocyte asymmetry develops during oogenesis and must be maintained during consecutive and obligatorily asymmetric oogonial divisions, which depending on the species lead to the formation of either oocyte alone or oocyte and nurse cell complex. In the following chapter, we summarize current knowledge on the asymmetric oogonial divisions in invertebrate (insects) and vertebrate (Xenopus) species.

摘要

在大多数动物中，卵母细胞/卵子在结构、分子和功能上都是不对称的。这种不对称是后续胚胎发育过程中完美受精和母体决定因素准确分离的先决条件。卵母细胞不对称性在卵子发生过程中形成，并且在连续且必然不对称的卵原细胞分裂过程中必须得以维持，这取决于物种，会导致单独形成卵母细胞或形成卵母细胞与滋养细胞复合体。在接下来的章节中，我们总结了关于无脊椎动物（昆虫）和脊椎动物（非洲爪蟾）物种中不对称卵原细胞分裂的现有知识。