Sadati Maryam S, Dastgheib Ladan, Aflaki Elham
Department of Dermatology, Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran -
Department of Dermatology, Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
G Ital Dermatol Venereol. 2017 Jun;152(3):308-310. doi: 10.23736/S0392-0488.17.04876-3.
Pyoderma gangrenosum (PG) is an uncommon ulcerative cutaneous disease, without any well-known specific and effective treatment. Here we report two patients with severe recalcitrant perineal pyoderma gangrenosum, successfully treated with low dose systemic tacrolimus. Tacrolimus can be a safe effective drug in the management of recalcitrant PG.
坏疽性脓皮病（PG）是一种罕见的溃疡性皮肤病，尚无任何知名的特效治疗方法。在此，我们报告两例严重顽固性会阴坏疽性脓皮病患者，经低剂量全身性他克莫司成功治疗。他克莫司在治疗顽固性PG方面可能是一种安全有效的药物。
