Romero-Brufau Santiago, Morlan Bruce W, Johnson Matthew, Hickman Joel, Kirkland Lisa L, Naessens James M, Huddleston Jeanne
Robert D. and Patricia E. Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, USA.
Health Care Policy and Research, Mayo Clinic, Rochester, MN, USA.
J Hosp Med. 2017 Apr;12(4):217-223. doi: 10.12788/jhm.2712.
The use of rapid response systems (RRS), which were designed to bring clinicians with critical care expertise to the bedside to prevent unnecessary deaths, has increased. RRS rely on accurate detection of acute deterioration events. Early warning scores (EWS) have been used for this purpose but were developed using heterogeneous populations. Predictive performance may differ in medical vs surgical patients.
To evaluate the performance of published EWS in medical vs surgical patient populations.
Retrospective cohort study.
Two tertiary care academic medical center hospitals in the Midwest totaling more than 1500 beds.
All patients discharged from January to December 2011.
None.
Time-stamped longitudinal database of patient variables and outcomes, categorized as surgical or medical. Outcomes included unscheduled transfers to the intensive care unit, activation of the RRS, and calls for cardiorespiratory resuscitation ("resuscitation call"). The EWS were calculated and updated with every new patient variable entry over time. Scores were considered accurate if they predicted an outcome in the following 24 hours.
All EWS demonstrated higher performance within the medical population as compared to surgical: higher positive predictive value (P < .0001 for all scores) and sensitivity (P < .0001 for all scores). All EWS had positive predictive values below 25%.
The overall poor performance of the evaluated EWS was marginally better in medical patients when compared to surgical patients. Journal of Hospital Medicine 2017;12:217-223.
旨在让具备重症监护专业知识的临床医生到床边以预防不必要死亡的快速反应系统(RRS)的使用有所增加。RRS依赖于对急性病情恶化事件的准确检测。早期预警评分(EWS)已用于此目的,但却是使用异质性人群开发的。在内科患者与外科患者中,预测性能可能有所不同。
评估已发表的EWS在内科与外科患者群体中的性能。
回顾性队列研究。
中西部地区两家拥有超过1500张床位的三级医疗学术医学中心医院。
2011年1月至12月出院的所有患者。
无。
按外科或内科分类的带有时间戳的患者变量和结局纵向数据库。结局包括非计划转入重症监护病房、RRS激活以及心肺复苏呼叫(“复苏呼叫”)。随着时间推移,随着每个新的患者变量输入计算并更新EWS。如果评分在接下来的24小时内预测了一个结局,则认为该评分是准确的。
与外科患者相比,所有EWS在内科患者群体中表现出更高的性能:更高的阳性预测值(所有评分P <.0001)和敏感性(所有评分P <.0001)。所有EWS的阳性预测值均低于25%。
与外科患者相比,所评估的EWS总体表现不佳,在内科患者中略好一些。《医院医学杂志》2017年;12:217 - 223。