Suppr超能文献

小肾肿物的流行病学及治疗脱节现象

Epidemiology of the Small Renal Mass and the Treatment Disconnect Phenomenon.

作者信息

Turner Robert M, Morgan Todd M, Jacobs Bruce L

机构信息

Department of Urology, University of Pittsburgh Medical Center, Mercy Professional Building, 1350 Centre Avenue, Suite G100A, Pittsburgh, PA 15219, USA.

Department of Urology, University of Michigan, 1500 E. Medical Center Drive, CCC 7308, Ann Arbor, MI 48109, USA.

出版信息

Urol Clin North Am. 2017 May;44(2):147-154. doi: 10.1016/j.ucl.2016.12.001. Epub 2017 Mar 14.

Abstract

The incidence of kidney cancer has steadily increased over recent decades, with most new cases now found when lesions are asymptomatic and small. This downward stage migration relates to the increasing use of abdominal imaging. Three public health epidemics-smoking, hypertension, and obesity-also play roles in the increase. Treatment mirrors the rise in incidence, with increasing interest in nephron-sparing therapies. Despite earlier detection and increasing treatment, the mortality rate has not decreased. This treatment disconnect phenomenon highlights the need to decrease unnecessary treatment of indolent tumors and address modifiable risk factors to reduce incidence and mortality.

摘要

近几十年来,肾癌的发病率稳步上升,现在大多数新病例是在病变无症状且较小的时候发现的。这种分期下移与腹部影像学检查的使用增加有关。吸烟、高血压和肥胖这三种公共卫生流行病也在发病率上升中起作用。治疗情况与发病率的上升相呼应,对保留肾单位疗法的兴趣日益增加。尽管检测更早且治疗增加,但死亡率并未下降。这种治疗脱节现象凸显了减少对惰性肿瘤的不必要治疗以及解决可改变的风险因素以降低发病率和死亡率的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/89ba/5407311/1264179262ce/nihms840131f1.jpg

相似文献

1
Epidemiology of the Small Renal Mass and the Treatment Disconnect Phenomenon.小肾肿物的流行病学及治疗脱节现象
Urol Clin North Am. 2017 May;44(2):147-154. doi: 10.1016/j.ucl.2016.12.001. Epub 2017 Mar 14.
4
Current Trends in Renal Surgery and Observation for Small Renal Masses.肾外科手术及小肾肿瘤观察的当前趋势
Urol Clin North Am. 2017 May;44(2):169-178. doi: 10.1016/j.ucl.2016.12.003. Epub 2017 Mar 14.
5
Epidemiology and risk factors for kidney cancer.肾癌的流行病学和危险因素。
Nat Rev Urol. 2010 May;7(5):245-57. doi: 10.1038/nrurol.2010.46.
8
Kidney cancer: the new landscape.肾癌:新态势
Curr Opin Urol. 2009 Mar;19(2):133-7. doi: 10.1097/MOU.0b013e328323f5ab.
9
Effects of obesity on immune responses to renal tumors.肥胖对肾肿瘤免疫反应的影响。
Immunol Res. 2014 Aug;59(1-3):211-9. doi: 10.1007/s12026-014-8533-0.

引用本文的文献

本文引用的文献

2
Cancer statistics, 2016.癌症统计数据,2016 年。
CA Cancer J Clin. 2016 Jan-Feb;66(1):7-30. doi: 10.3322/caac.21332. Epub 2016 Jan 7.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验