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冠心病中的肥胖:一个未得到解决的行为风险因素。

Obesity in coronary heart disease: An unaddressed behavioral risk factor.

机构信息

University of Vermont College of Medicine, Division of Cardiology, Burlington, VT 05405, United States.

University of Vermont College of Medicine, Division of Cardiology, Burlington, VT 05405, United States.

出版信息

Prev Med. 2017 Nov;104:117-119. doi: 10.1016/j.ypmed.2017.04.013. Epub 2017 Apr 13.

DOI:10.1016/j.ypmed.2017.04.013
PMID:28414064
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5640469/
Abstract

Obesity is an independent risk factor for the development and progression of coronary heart disease (CHD). Over 80% of patients with CHD are overweight or obese. While obesity is often considered a relatively "minor" CHD risk factor, weight loss is a broadly effective risk-factor intervention. Weight loss can profoundly influence a number of "major" risk factors including: hypertension, dyslipidemia and insulin resistance/type 2 diabetes mellitus. Despite its prominence as a risk factor most cardiac rehabilitation (CR) programs do not have a specific, targeted intervention to assist patients with weight loss. Consequently, the weight loss that occurs during CR is quite small and unlikely to appreciably alter risk factors. Relying on CR associated exercise as a sole intervention is an ineffective strategy to promote weight loss. There is evidence, however, that behavioral weight loss (BWL) interventions can be effectively employed in the CR setting. In contrast to programs that do not offer a targeted intervention, studies show that participants in CR-related BWL programs lose significantly more weight. The additional weight loss from the BWL intervention is associated with greater improvements in insulin sensitivity and other components of the metabolic syndrome such as hypertension and lipid abnormalities. As a means of maximizing CHD risk factor reduction CR programs need to incorporate BWL programs as a standard programming for overweight/obese patients.

摘要

肥胖是冠心病(CHD)发展和进展的独立危险因素。超过 80%的 CHD 患者超重或肥胖。虽然肥胖通常被认为是 CHD 的一个相对“次要”的危险因素,但减肥是一种广泛有效的危险因素干预措施。减肥可以深刻影响许多“主要”危险因素,包括:高血压、血脂异常和胰岛素抵抗/2 型糖尿病。尽管肥胖作为一个危险因素很突出,但大多数心脏康复(CR)计划并没有专门针对减肥的特定干预措施来帮助患者。因此,CR 期间发生的体重减轻非常小,不太可能明显改变危险因素。仅仅依靠与 CR 相关的运动作为单一干预措施是促进减肥的无效策略。然而,有证据表明,行为减肥(BWL)干预措施可以在 CR 环境中有效实施。与不提供针对性干预的计划相比,研究表明,参与 CR 相关 BWL 计划的参与者体重明显减轻更多。BWL 干预带来的额外体重减轻与胰岛素敏感性和代谢综合征的其他成分(如高血压和脂质异常)的更大改善相关。作为最大限度降低 CHD 危险因素的一种手段,CR 计划需要将 BWL 计划纳入超重/肥胖患者的标准编程中。

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Referral to a Commercial Weight Management Program in Patients With Coronary Heart Disease: A PILOT STUDY IN THE NETHERLANDS.冠心病患者转诊至商业体重管理项目:荷兰的一项试点研究。
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Remission of recently diagnosed type 2 diabetes mellitus with weight loss and exercise.近期诊断的2型糖尿病通过体重减轻和运动实现缓解。
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