富血小板血浆对犬正畸牙齿移动的影响。
Effect of platelet-rich plasma on orthodontic tooth movement in dogs.
作者信息
Rashid A, ElSharaby F A, Nassef E M, Mehanni S, Mostafa Y A
机构信息
Department of Orthodontics and Dentofacial Orthopedics, Fayoum University, Fayoum, Egypt.
Department of Orthodontics and Dentofacial Orthopedics, Cairo University, Cairo, Egypt.
出版信息
Orthod Craniofac Res. 2017 May;20(2):102-110. doi: 10.1111/ocr.12146.
OBJECTIVES
To evaluate the effect of platelet-rich plasma (PRP) on the rate of orthodontic tooth movement.
METHODS
The sample comprised six skeletally mature male mongrel dogs. The maxillary second premolar in each dog was extracted bilaterally. PRP was prepared and injected around the first premolar in one randomly selected maxillary quadrant while the other quadrant served as the control. Coil springs (150 g) were used to distalize the first premolars for 63 days using TAD as anchorage.
RESULTS
Total maxillary tooth movement was significantly faster on the experimental than on the control side.
CONCLUSION
Local injection of PRP in the present animal study resulted in accelerated orthodontic tooth movement with no obvious clinical or microscopic side effects.
目的
评估富血小板血浆（PRP）对正畸牙齿移动速率的影响。
方法
样本包括6只骨骼成熟的雄性杂种犬。每只犬双侧拔除上颌第二前磨牙。制备PRP并注射到随机选择的一个上颌象限的第一前磨牙周围，而另一个象限作为对照。使用螺旋弹簧（150 g）以微型钛钉作为支抗将第一前磨牙远中移动63天。
结果
上颌牙齿的总移动在实验侧明显快于对照侧。
结论
在本动物研究中局部注射PRP导致正畸牙齿移动加速，且无明显的临床或微观副作用。
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