Winterleitner H, Rella W, Eibl M, Krepler P
Oncology. 1978;35(6):258-62. doi: 10.1159/000225300.
In 35 children with acute lymphatic or undifferentiated leukemia, immunological properties of normal lymphocytes and lymphoblasts were investigated. In most cases the number of circulating normal lymphocytes with surface or B markers and delayed type hypersensitivity was depressed. On the other hand, the response to mitogenic stimulation with PHA as well as the antibody and immunoglobulin serum concentrations were found to be normal. Lymphoblasts did not exhibit surface receptors in any but four patients, who showed 10--18% of leukemic blasts being positive for E-rosette formation at 0 degree but not at 37 degrees.
对35例急性淋巴细胞性或未分化型白血病患儿的正常淋巴细胞和淋巴母细胞的免疫特性进行了研究。多数情况下，具有表面或B标记以及迟发型超敏反应的循环正常淋巴细胞数量减少。另一方面，发现对PHA促有丝分裂刺激的反应以及抗体和免疫球蛋白血清浓度均正常。除4例患者外，淋巴母细胞未表现出表面受体，这4例患者在0℃时白血病母细胞中有10%-18%形成E玫瑰花结呈阳性，但在37℃时则不然。
