Vieira Ana Claudia, Alvarenga Maria Joana, Santos Jose Carlos, Silva Alberto Mello
Pneumologia, Hospital de Egas Moniz, Lisboa, Portugal.
Medicina Interna I, Hospital de Egas Moniz, Lisboa, Portugal.
BMJ Case Rep. 2017 Apr 22;2017:bcr-2016-218001. doi: 10.1136/bcr-2016-218001.
Cholestasis has numerous causes. We present the case of a 78-year-old man with a common diagnosis in this age group and gender but with an unusual presentation. There are only 11 articles published of patients with jaundice due to a paraneoplastic syndrome associated with prostate cancer. Interleukin 6 and other proinflammatory cytokines appear to contribute to the pathophysiology of this syndrome. Our patient remains symptom free 4 months after treatment initiation.