胆淤积性黄疸作为前列腺癌的副肿瘤表现，因类固醇治疗而加重。
Cholestatic Jaundice as a Paraneoplastic Manifestation of Prostate Cancer Aggravated by Steroid Therapy.
出版信息
Med Princ Pract. 2018;27(2):197-200. doi: 10.1159/000486717. Epub 2018 Jan 10.
Abstract
OBJECTIVE
To report a rare case of paraneoplastic jaundice as a manifestation of prostate cancer.
CLINICAL PRESENTATION AND INTERVENTION
We report on a case of paraneoplastic syndrome in a 72-year-old man with prostate cancer that manifested with idiopathic jaundice. Although steroids can be used as treatment in patients with prostate cancer, they could exacerbate paraneoplastic jaundice. The jaundice that flared up after treatment with 40 mg prednisone was improved with antiandrogen treatment.
CONCLUSION
Physicians should be aware of the possibility of paraneoplastic jaundice in patients with prostate cancer. Appropriate antiandrogen therapy should be considered for paraneoplastic jaundice in these patients.
摘要
目的
报告一例前列腺癌表现为癌旁性黄疸的罕见病例。
临床表现及干预
我们报告了一例 72 岁前列腺癌患者的癌旁综合征病例，其表现为特发性黄疸。虽然皮质类固醇可用于治疗前列腺癌患者，但它们可能使癌旁性黄疸恶化。用 40mg 泼尼松治疗后黄疸加重，用抗雄激素治疗后得到改善。
结论
医生应意识到前列腺癌患者发生癌旁性黄疸的可能性。对于这些患者的癌旁性黄疸，应考虑适当的抗雄激素治疗。
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