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本文引用的文献

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Developing a framework for assessing chemical respiratory sensitization: A workshop report.制定化学物质呼吸道致敏评估框架:研讨会报告
Regul Toxicol Pharmacol. 2016 Oct;80:295-309. doi: 10.1016/j.yrtph.2016.06.006. Epub 2016 Jul 7.
2
'No touch' technologies for environmental decontamination: focus on ultraviolet devices and hydrogen peroxide systems.用于环境净化的“非接触式”技术:聚焦于紫外线设备和过氧化氢系统。
Curr Opin Infect Dis. 2016 Aug;29(4):424-31. doi: 10.1097/QCO.0000000000000284.
3
Effectiveness of ultraviolet devices and hydrogen peroxide systems for terminal room decontamination: Focus on clinical trials.紫外线设备和过氧化氢系统用于终末病房消毒的有效性:聚焦于临床试验
Am J Infect Control. 2016 May 2;44(5 Suppl):e77-84. doi: 10.1016/j.ajic.2015.11.015.
4
Do chronic workplace irritant exposures cause asthma?长期接触工作场所的刺激性物质会导致哮喘吗?
Curr Opin Allergy Clin Immunol. 2016 Apr;16(2):75-85. doi: 10.1097/ACI.0000000000000247.
5
Genome-Wide Association Study Identifies Novel Loci Associated With Diisocyanate-Induced Occupational Asthma.全基因组关联研究确定了与二异氰酸酯诱导的职业性哮喘相关的新基因座。
Toxicol Sci. 2015 Jul;146(1):192-201. doi: 10.1093/toxsci/kfv084. Epub 2015 Apr 26.
6
Web based listing of agents associated with new onset work-related asthma.基于网络的与新发职业性哮喘相关的因素列表
Respir Med. 2015 May;109(5):625-31. doi: 10.1016/j.rmed.2015.03.004. Epub 2015 Mar 31.
7
Work-related asthma—22 states, 2012.与工作相关的哮喘——2012年,22个州
MMWR Morb Mortal Wkly Rep. 2015 Apr 10;64(13):343-6.
8
Cleaning and disinfecting environmental surfaces in health care: Toward an integrated framework for infection and occupational illness prevention.医疗机构环境表面的清洁与消毒:构建感染与职业疾病预防综合框架
Am J Infect Control. 2015 May 1;43(5):424-34. doi: 10.1016/j.ajic.2015.01.029. Epub 2015 Mar 16.
9
Occupational asthma after exposure to ortho-phthalaldehyde (OPA).接触邻苯二甲醛(OPA)后发生的职业性哮喘。
Occup Environ Med. 2015 May;72(5):381. doi: 10.1136/oemed-2015-102847. Epub 2015 Mar 16.
10
Asthma history, job type and job changes among US nurses.美国护士的哮喘病史、工作类型及工作变动情况
Occup Environ Med. 2015 Jul;72(7):482-8. doi: 10.1136/oemed-2014-102547. Epub 2015 Feb 24.

职业性哮喘循证转化为政策的机遇与障碍

Opportunities and obstacles in translating evidence to policy in occupational asthma.

机构信息

Department of Medicine, University Health Network, University of Toronto, Ontario, Canada; Department of Medicine, University of Toronto, Ontario, Canada; Department of Public Health Sciences, University of Toronto, Ontario, Canada.

UNC Charlotte, Department of Public Health Sciences, Charlotte, NC.

出版信息

Ann Epidemiol. 2018 Jun;28(6):392-400. doi: 10.1016/j.annepidem.2017.03.002. Epub 2017 Mar 31.

DOI:10.1016/j.annepidem.2017.03.002
PMID:28434545
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5953844/
Abstract

PURPOSE

Occupational asthma (OA), a common respiratory disorder in Western countries, is caused by exposures at the workplace. It is part of a broader definition of work-related asthma (WRA) that also includes pre-existing asthma aggravated by substances present in the workplace environment, and it is potentially preventable. The purpose of this paper is to illustrate preventive measures for occupational asthma by case studies.

METHODS

In three case studies we discuss preventive measures that have been associated with reductions in incidence of occupational asthma from natural rubber latex and from diisocyanates as supported by published literature. We also discuss challenges in relation to asthma from cleaning products in healthcare work.

RESULTS AND CONCLUSIONS

Several preventive measures have been associated with reduction in incidence of occupational asthma from natural rubber latex and from diisocyanates, and may provide lessons for prevention of other causes of occupational asthma. Cleaning products remain an unresolved problem at present with respect to asthma risks but potential measures include the use of safer products and safer applications such as avoidance of spray products, use of occupational hygiene methods such as improving local ventilation, and when appropriate, the use of personal protective devices.

摘要

目的

职业性哮喘(OA)是西方国家常见的呼吸道疾病,由工作场所暴露引起。它是工作相关哮喘(WRA)更广泛定义的一部分,也包括因工作场所环境中存在的物质而加重的预先存在的哮喘,并且是可以预防的。本文的目的是通过案例研究说明职业性哮喘的预防措施。

方法

在三个案例研究中,我们讨论了一些预防措施,这些措施与天然橡胶乳胶和异氰酸酯引起的职业性哮喘发病率降低有关,这得到了已发表文献的支持。我们还讨论了与医疗保健工作中清洁产品相关的哮喘问题。

结果和结论

一些预防措施与天然橡胶乳胶和异氰酸酯引起的职业性哮喘发病率降低有关,可能为预防其他职业性哮喘原因提供了经验教训。清洁产品目前仍是哮喘风险方面未解决的问题,但潜在的措施包括使用更安全的产品和更安全的应用,例如避免喷雾产品,使用职业卫生方法,例如改善局部通风,以及在适当的情况下使用个人防护设备。