转移性少突胶质细胞瘤继发骨硬化症
Osteosclerosis Secondary to Metastatic Oligodendroglioma.
作者信息
Maloney Patrick R, Yamaki Vitor Nagai, Kumar Ravi, Johnson Derek, Hunt Christopher, Jentoft Mark E, Clarke Michelle
机构信息
Departments of Neurosurgery, Mayo Clinic, College of Medicine, Rochester, MN, USA.
Neurology, Mayo Clinic, College of Medicine, Rochester, MN, USA.
出版信息
Rare Tumors. 2017 Mar 31;9(1):6837. doi: 10.4081/rt.2017.6837. eCollection 2017 Mar 24.
This paper reviews a case of metastatic 1p/19q codeleted oligodendrioglioma causing diffuse osteosclerosis and pain. Primary central nervous system (CNS) tumors rarely metastasize outside the CNS, and metastatic oligodendroglioma is rarer still. The patient in this study had relief of pain after being treated with temozolomide. We discuss this rare presentation and potential treatment options, and review the literature in regards to metastatic oligodendrogliomas.
本文回顾了一例导致弥漫性骨硬化和疼痛的1p/19q共缺失转移性少突胶质细胞瘤病例。原发性中枢神经系统（CNS）肿瘤很少转移至CNS以外，而转移性少突胶质细胞瘤更为罕见。本研究中的患者在接受替莫唑胺治疗后疼痛缓解。我们讨论了这种罕见的表现及潜在的治疗选择，并回顾了有关转移性少突胶质细胞瘤的文献。
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