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利培酮治疗一名发育障碍患者的皮肤搔抓症取得改善

Improvement in Excoriation (Skin-Picking) with use of Risperidone in a Patient with Developmental Disability.

作者信息

Roi Cody, Bazzano Alessandra

机构信息

Department of Child and Adolescent Psychiatry, Louisiana State University School of Medicine, New Orleans, LA.

Department of Global Community Health and Behavioral Sciences, Tulane University School of Public Health and Tropical Medicine, New Orleans, LA, USA.

出版信息

Pediatr Rep. 2017 Mar 22;9(1):6946. doi: 10.4081/pr.2017.6946.

Abstract

Patients with Autism Spectrum Disorder present with a heterogeneous mix of features beyond the core symptoms of the disorder. These features can be emotional, cognitive or behavioral. Behavioral symptoms often include self-injury, and this may take the form of repetitive skin-picking. The prevalence of skin-picking disorder in Autism is unknown. Skin-picking may lead to significant medical and psychosocial complications. Recent data suggest that behavioral interventions may be more effective than medications at reducing skin-picking in neurotypical patients. In this case, an 11-year-old male with intellectual disability and autistic spectrum disorder, with self-injurious skin-picking, was treated with risperidone with complete resolution of skin-picking symptoms. risperidone has been approved for irritability and aggression in Autistic spectrum disorder, and may be a valuable treatment option for skin-picking in pediatric patients with developmental disabilities.

摘要

自闭症谱系障碍患者除了该障碍的核心症状外,还表现出各种各样的特征。这些特征可能是情感、认知或行为方面的。行为症状通常包括自我伤害,这可能表现为反复抠皮肤。自闭症患者中抠皮肤障碍的患病率尚不清楚。抠皮肤可能会导致严重的医学和心理社会并发症。最近的数据表明,行为干预在减少典型神经发育患者的抠皮肤行为方面可能比药物更有效。在这个案例中,一名患有智力障碍和自闭症谱系障碍且有自我伤害性抠皮肤行为的11岁男性,接受了利培酮治疗,抠皮肤症状完全缓解。利培酮已被批准用于治疗自闭症谱系障碍中的易激惹和攻击行为,对于有发育障碍的儿科患者的抠皮肤行为可能是一种有价值的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aad5/5379223/4b2b61eb280d/pr-2017-1-6946-g001.jpg

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