韩国城市成年人中糖尿病与环境空气污染关系的性别差异
Gender-dependent Differences in the Relationship between Diabetes Mellitus and Ambient Air Pollution among Adults in South Korean Cities.
作者信息
Sohn Dongwook, Oh Hyunjin
机构信息
Dept. of Architectural Engineering, Yonsei University, Seoul, South Korea.
Dept. of Nursing, Gachon University, Incheon, South Korea.
出版信息
Iran J Public Health. 2017 Mar;46(3):293-300.
BACKGROUND
Air pollution has been a serious public health threat worldwide. It has been linked to pulmonary and cardiovascular diseases but is also believed to contribute to air-pollution-mediated cardiometabolic disease such as diabetes. We investigated the relationship between type 2 diabetes mellitus (DM2) and air pollution in densely developed urban settings in South Korea, using national epidemiologic data.
METHODS
The analysis focused on examining gender-related differences in the relationship between DM 2 and air pollutants, specifically particulate matter ≤ 10μm (PM) and sulfur dioxide (SO). To assess the relationship between DM and exposure to PM and SO, multivariate logistic regression models were developed using the 2012 Korea Community Health Survey data and the ambient air pollution data in South Korean cities at both - and levels.
RESULTS
The commonly encountered levels of PM and SO may be associated with DM 2 prevalence in South Korea but it appears there may be gender differences. In particular, exposure to either PM or SO was significantly related to the prevalence of DM 2 among women but not among men.
CONCLUSION
These findings provide new evidence of an association between air pollution and the risk of diabetes in urbanized areas of South Korea.
背景
空气污染一直是全球严重的公共卫生威胁。它与肺部和心血管疾病有关，但也被认为会导致空气污染介导的心脏代谢疾病，如糖尿病。我们利用国家流行病学数据，调查了韩国人口密集的城市地区2型糖尿病（DM2）与空气污染之间的关系。
方法
分析重点在于研究DM2与空气污染物（特别是≤10μm颗粒物（PM）和二氧化硫（SO））之间关系中的性别差异。为评估DM与PM和SO暴露之间的关系，我们使用2012年韩国社区健康调查数据以及韩国城市在市和道两级的环境空气污染数据，建立了多元逻辑回归模型。
结果
韩国常见的PM和SO水平可能与DM2患病率有关，但似乎存在性别差异。特别是，暴露于PM或SO与女性DM2患病率显著相关，而与男性无关。
结论
这些发现为韩国城市化地区空气污染与糖尿病风险之间的关联提供了新证据。
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