Misrani Afzal, Tabassum Sidra, Long Cheng
School of Life Sciences, South China Normal University, Guangzhou 510631, China.
Institute of Brain Science, South China Normal University, Guangzhou 510631, China.
Sheng Li Xue Bao. 2017 Apr 25;69(2):196-206.
Oxytocin (OXT) is a neuropeptide that plays a pivotal role among species peripherally and centrally. It recently has attracted much attention for its involvement in anxiety-related behavior, stress regulation, social behavior and various neuropsychiatric disorders. OXT is one of the important mediators of emotional and social behaviors such as maternal behavior, fear extinction, social support, happiness, and trust. It is also involved in learning and memory process. The recent progresses in OXT system have put this neuropeptide as an important psychotherapeutic intervention for various psychiatric disorders such as stress, anxiety disorders, social phobia, postpartum depression, bipolar disorder, autism, and schizophrenia. In this review, we highlight OXT's contributions to various physiological functions and psychological disorders and discuss its potential use as a therapeutic agent.
催产素（OXT）是一种神经肽，在物种的外周和中枢发挥着关键作用。最近，它因其参与焦虑相关行为、应激调节、社会行为以及各种神经精神疾病而备受关注。催产素是情绪和社会行为（如母性行为、恐惧消退、社会支持、幸福感和信任）的重要调节因子之一。它还参与学习和记忆过程。催产素系统的最新进展使这种神经肽成为治疗各种精神疾病（如应激、焦虑症、社交恐惧症、产后抑郁症、双相情感障碍、自闭症和精神分裂症）的重要心理治疗干预手段。在本综述中，我们将重点介绍催产素对各种生理功能和心理障碍的作用，并讨论其作为治疗药物的潜在用途。
