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儿童生长生理学:激素调节

The Physiology of Childhood Growth: Hormonal Regulation.

作者信息

Benyi Emelie, Sävendahl Lars

出版信息

Horm Res Paediatr. 2017;88(1):6-14. doi: 10.1159/000471876. Epub 2017 Apr 24.

DOI:10.1159/000471876
PMID:28437784
Abstract

The growth patterns of a child changes from uterine life until the end of puberty. Height velocity is highest in utero and declines after birth until puberty when it rises again. Important hormonal regulators of childhood growth are growth hormone, insulin-like growth factor 1, sex steroids, and thyroid hormone. This review gives an overview of these hormonal regulators of growth and their interplay with nutrition and other key players such as inflammatory cytokines.

摘要

儿童的生长模式从子宫内发育阶段到青春期结束会发生变化。宫内生长速度最快,出生后下降,直至青春期再次上升。儿童生长的重要激素调节因子包括生长激素、胰岛素样生长因子1、性类固醇和甲状腺激素。本文综述了这些生长激素调节因子及其与营养和其他关键因素(如炎性细胞因子)的相互作用。

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